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Genitourinary Cancer

Genitourinary Cancer

Impact of Time to Castration Resistance on Cytoreductive Radiotherapy in Metastatic Castration-Resistant Prostate Cancer

This study aimed to identify the value of local radiotherapy and potential candidates for metastatic castration-resistant prostate cancer.

Frontiers in Oncology
12/04/2020
Genitourinary Medical Oncology Expert Opinion Survey Regarding Treatment Management in COVID-19 Pandemic

The specific changes in the management of genitourinary cancers in different cancer centers due to COVID-19 are not known and some clinical scenarios remain controversial.

01/07/2021
Bayesian Network Analysis of Open, Laparoscopic, and Robot-Assisted Radical Cystectomy for Bladder Cancer

Study investigators perform the direct and network meta-analysis to evaluate the safety and efficacy of robot-assisted versus laparoscopic versus open radical cystectomy for bladder cancer.

12/24/2020

Fifteen-MiRNA-Based Signature Is a Reliable Prognosis-Predicting Tool for Prostate Cancer Patients

Recurrence is a major problem for prostate cancer patients, thus, identifying prognosis-related markers to evaluate clinical outcomes is essential.

01/01/2021
A Clinical Evaluation of Enzalutamide in Metastatic Castration-Sensitive Prostate Cancer: Guiding Principles for Treatment Selection and Perspectives on Research

This publication comprehensively analyzes the clinical evidence and guiding principles of enzalutamide use in castration-sensitive prostate cancer.

12/29/2020
Epidemiology and survival outcome of adult kidney, bladder, and prostate rhabdomyosarcoma: A SEER database analysis

Study investigators perform an analysis of all adult RMS cases reported in SEER database to understand prognostic factors among kidney, bladder, and prostate RMS.

12/04/2020
Early Salvage Radiotherapy Bests Adjuvant Treatment for Prostate Cancer

Adjuvant radiotherapy following radical prostatectomy does not improve event-free survival in men with localized or locally advanced prostate cancer and should not be considered...

Oncology Times - Latest Articles
12/20/2020
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Origin of Subsequent Malignant Neoplasms in Patients with History of Testicular Germ Cell Tumor

This study investigates the genetic landscape and cellular origins of cancers that develop later in life after treatment for TGCT and found evidence that a common progenitor cell...

Cancers
12/14/2020
A novel imaging based Nomogram for predicting post-surgical biochemical recurrence and adverse pathology of prostate cancer from pre-operative bi-parametric MRI

Investigators developed and validated an integrated radiomic-clinicopathologic nomogram for post-surgical biochemical recurrence free survival and adverse pathology prediction...

12/13/2020
Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy

Only a subgroup of patients with muscle-invasive bladder cancer are responders toward cisplatin-based chemotherapy and PD-L1 blockade immunotherapy.

12/17/2020
Evaluation of cytokine expression and circulating immune cell subsets as potential parameters of acute radiation toxicity in prostate cancer patients

The aim of research was to evaluate the possible clinical value of the associations between clinical, physical, and biological factors, and risk for development of acute radiotoxicity in patients..

Scientific Reports
11/04/2020
Mobile Health App for Prostate Cancer Patients on Androgen Deprivation Therapy: Qualitative Usability Study

This study aimed to evaluate the usability and patient experience of a newly developed mHealth app among prostate cancer patients on ADT and physicians’ beliefs about the potential benefits of...

11/03/2020
Genitourinary Syndrome of Menopause: Current Treatment Options in Breast Cancer Survivors – Systematic Review

Breast cancer survivors usually receive treatments which lead to persistent oestrogen suppression, which may cause atrophic vaginitis in a large proportion of these women. 

Maturitas
01/01/2021
A Comparison of Genitourinary Society Pathology and International Society of Urological Pathology Prostate Cancer Guidelines.

In 2019, GUPS and ISUP held their own consensus conferences on prostate cancer grading, with separately published manuscripts.

European Urology
11/11/2020
The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future.

The objective of this study was to provide an evidence-informed, expert-derived review of genitourinary cancer care moving forward following the initial COVID-19 pandemic.

European Urology
09/04/2020
Pilot study of fractional CO2 laser therapy for genitourinary syndrome of menopause in gynecologic cancer survivors

This study evaluated the efficacy of fractional CO2 laser treatments in gynecologic cancer survivors with GSM.

Maturitas
02/01/2021
Surgical Management of Genitourinary Cancer Liver Metastases.

Genitourinary cancers are common. Liver metastases from genitourinary uncommon

Surgical Oncology Clinics of North America
01/01/2021
Common germline-somatic variant interactions in advanced urothelial cancer

The prevalence and biological consequences of deleterious germline variants in urothelial cancer are not fully characterized.

12/03/2020
Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis

The association between blood pressure and bladder cancer risk remains unclear with confounding by smoking being of particular concern.

PLOS ONE
11/25/2020
A review of current advancements and limitations of artificial intelligence in genitourinary cancers

In the realm of genitourinary cancers, AI has had particular success in improving the diagnosis and treatment of prostate, renal, and bladder cancers.

10/15/2020
Management of urologic cancers during the pandemic and potential impact of treatment deferrals on outcomes

This study summarized the prepandemic literature on deferred surgery for GU cancers and risk of disease progression.

10/28/2020
The Immune Microenvironment in Penile Cancer and Rationale for Immunotherapy

This review described the penile cancer microenvironment, and summarized the rationale for immunotherapy in penile cancer patients.

10/17/2020
Discrepancies between genitourinary cancer patients' and clinicians' characterization of the Eastern Cooperative Oncology Group performance status.

This study was designed to describe the patient‐reported performance status and the provider‐reported PS.

Cancer
10/02/2020
Development and Validation of a Comprehensive Multivariate Dosimetric Model for Predicting Late Genitourinary Toxicity Following Prostate Cancer Stereotactic Body Radiotherapy.

This study sought to develop a multivariate model that predicts CTCAE late grade 2 or greater genitourinary toxicity by interrogating the entire DVH from a large cohort of prostate cancer...

Frontiers in Oncology
05/20/2020
Landscape of somatic DNA damage repair (DDR) gene mutations in genitourinary cancer in China.

In this study, the authors assessed DDR GAs for better understanding therapeutic implications.

Journal of Clinical Oncology
05/20/2020
Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey

This study's purpose was to survey urologic clinicians regarding interpretation of and practice patterns in relation to emerging aspects of prostate cancer grading, including...

Urologic Oncology-seminars and Original Investigations
09/15/2020
Assessing Genitourinary Cancer Clinical Trial Accrual Sufficiency Using Archived Trial Data

Clinical trials often fail to reach their anticipated end points, most frequently because of poor accrual.

JCO clinical cancer informatics
07/15/2020
Update on Circulating Tumor Cells in Genitourinary Tumors with Focus on Prostate Cancer.

Current developments in the treatment of genitourinary tumors underline unmet clinical need for biomarkers to improve decision-making a challenging setting.

Cells
06/19/2020
A comparison of general, genitourinary, bowel, and sexual quality of life among long term survivors of prostate, bladder, colorectal, and lung cancer.

A comparison of general, genitourinary, bowel, and sexual quality of life among long term survivors of prostate, bladder, colorectal, and lung cancer.

Journal of Geriatric Oncology
07/29/2020
The scope, presentation, and management of genitourinary complications in patients presenting with high-grade urethral complications after radiotherapy for prostate cancer.

The objective of this study is to describe the presentation, scope, and management of genitourinary complications in patients referred for high-grade urethral complications or sphincter weakness in

Cuaj-canadian Urological Association Journal
07/17/2020
A competing risk analysis of death patterns in male genitourinary cancer.

This work is aimed to explore the death patterns among male genitourinary cancer patients due to other causes. The occurrence of death not related to cancer is defined as competing risk.

Cancer reports (Hoboken, N.J.)
08/01/2020

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