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Head And Neck Cancer

Head And Neck Cancer

Endoscopic Surveillance for Metachronous Esophageal Squamous Cell Neoplasms among Head and Neck Cancer Patients

This study recommends image enhanced endoscopy including Lugol chromoendoscopy as the screening tool for incident HNSCC patients.

Cancers
12/18/2020
Risk Factors for Osteoradionecrosis of the Jaw in Patients with Head and Neck Squamous Cell Carcinoma

This study evaluates factors associated with ORNJ in patients with HNSCC, focusing on jaw-related dose–volume histogram parameters.

01/05/2021
Prehabilitation in Head and Neck Cancer Patients

Dysphagia is one consequence of head and neck cancer that has a significant impact on quality of life for head and neck cancer survivors.

01/06/2021

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Landscape of natural killer cell activity in head and neck squamous cell carcinoma

This study reviews the activity of NK cells in HNSCC, paying special attention to the role of environmental and genetic determinants of NK cell antitumor function.

12/21/2020
Research progress of radiation-induced hypothyroidism in head and neck cancer

This paper reviews the factors related to hypothyroidism after radiotherapy in patients with head and neck cancer to facilitate the prevention of radiation-induced hypothyroidism and...

01/01/2021
Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

The identification and validation of strategies to individualize therapy of patients with head and neck squamous cell carcinoma require cellular and animal models that accurately represent...

Cancers
12/12/2020
NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma, which is common and lethal.

Cells
12/12/2020
Molecular margins in head and neck cancer: Current techniques and future directions

Complete tumor extirpation with clear surgical margins remains a central tenet of oncologic head and neck surgery.

Oral Oncology
11/01/2020
Impact of treatment delay due to the pandemic of COVID-19 on the efficacy of immunotherapy in head and neck cancer patients

This study retrospectively analyzed 24 HNC patients treated with immune checkpoint inhibitors in our cancer institute prior to the outbreak of COVID-19 who were re-evaluated after...

12/11/2020
Radiomic features based on Hessian index for prediction of prognosis in head-and-neck cancer patients

This study demonstrated the usefulness of radiomic features based on the Hessian index of differential topology for the prediction of prognosis prior to treatment in HNC patients.

Scientific Reports
12/04/2020
Comprehensive Geriatric Assessment: A Case Report on Personalizing Cancer Care of an Older Adult Patient With Head and Neck Cancer.

This article aims to present comprehensive geriatric as an approach to personalizing care for older adults with cancer. 

Clinical Journal of Oncology Nursing
10/01/2020
Vitamin D in Head and Neck Cancer: a Systematic Review

This systematic literature review aimed to determine whether vitamin D deficiency is related to head and neck cancer etiology and outcome.

11/20/2020
Photoacoustic and Magnetic Resonance Imaging of Hybrid Manganese Dioxide-Coated Ultra-Small NaGdF4 Nanoparticles for Spatiotemporal Modulation of Hypoxia in Head and Neck Cancer

Tumor hypoxia is a documented negative prognostic factor that contributes to treatment resistance in head and neck cancer.

Cancers
11/06/2020
Toxicity syndrome and early competing deaths in head-and-neck cancer undergoing radiation therapy: Observation and hypothesis.

Radiotherapy and/or CRT is the mainstay for treatment of LAHNC. Sepsis remains a poorly understood and unrecognized event in cancer.

Medical Hypotheses
10/01/2020
STAT3 as a predictive biomarker in head and neck cancer: A validation study.

LAHNSCC treatment consists of radiotherapy (RT) alone or CCRT. CCRT is accompanied by substantially more toxicity than RT alone.

Pathology Research and Practice
11/01/2020
Institution-Specific Strategies for Head and Neck Oncology Triage During the COVID-19 Pandemic

This work seeks to better understand the triage strategies employed by head and neck oncologic surgical divisions during the initial phases of the COVID-19 outbreak.

12/04/2020
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

The independent effects of smoking and alcohol in head and neck cancer are not clear, given the strong association between these risk factors.

11/27/2020
The Clinical Significance of Dickkopf Wnt Signaling Pathway Inhibitor Gene Family in Head and Neck Squamous Cell Carcinoma

This study analyzed the expression of different DKK family members in patients with HNSCC and the relationships between their expression and clinical parameters, using...

11/26/2020
Extracellular Vesicles in Head and Neck Cancer: A Potential New Trend in Diagnosis, Prognosis, and Treatment

This study discussed the functionality of EVs in HNCs and their clinical potential with regards to biomarker and therapeutic capabilities.

International Journal of Molecular Sciences
11/04/2020
Awareness of Human Papillomavirus and Its Oncogenic Potential in Head and Neck Cancer among Students: Still More Questions than Answers

In the past years, HPV has been proved to be an important risk factor for HNSCCs, especially in the oropharynx.

International Journal of Environmental Research and Public Health
11/22/2020
Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis

This meta-analysis examined the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with HNC.

10/22/2020
Challenges in diagnosing head and neck cancer in primary health care.

The low incidence of HNC renders its detection challenging for a general practitioner in primary health care.

Annals of Medicine
01/01/2021
Prognostic significance of dynamic changes in lymphocyte-to-monocyte ratio in patients with head and neck cancer treated with radiotherapy: results from a large cohort study

This study sought to investigate whether dynamic changes in lymphocyte-to-monocyte ratio occurring during the course of RT may have prognostic value in patients with HNC.

Radiotherapy and Oncology
01/01/2021
Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients.

The purpose of this retrospective case study is to identify potential prognostic biomarkers in patients with HNSCC including APE1...

Oral Oncology
12/01/2020
Using the Glasgow Benefit Inventory questionnaire to quantify the health benefits of lymphoedema treatment in patients with head and neck cancer

The aim of this study was to quantify the health benefits of lymphoedema treatment using the Glasgow Inventory Benefit questionnaire, in patients with a history of treated head and neck cancer.

Applied Cancer Research
12/01/2020
Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19

The impact of COVID-19 on patients with cancer is emerging, but data are urgently needed for HNC patients or survivors who are inherently high-risk for severe illness and...

Oral Oncology
11/06/2020
Association of Immigration Status and Chinese and South Asian Ethnicity With Incidence of Head and Neck Cancer.

This study separates the independent associations of ethnicity and immigration with HNC incidence and identifies certain high-risk ethnocultural groups.

Archives of Otolaryngology-head &amp
11/05/2020
Electronic Cigarettes and Head and Neck Cancer Risk—Current State of Art

This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer.

Cancers
11/05/2020
State Medicaid expansion status, insurance coverage and stage at diagnosis in head and neck cancer patients.

This study aimed to quantify associations between state Medicaid expansions and changes in insurance coverage rates and stage at diagnosis of HNC.

Oral Oncology
11/01/2020
p53-dependent glutamine usage determines susceptibility to oxidative stress in radioresistant head and neck cancer cells.

Thus, p53 status may be an important biomarker for selecting cancer treatment strategies, including metabolic drugs and ROS-inducing agents, for recurrent cancers after...

Cellular Signalling
01/01/2021
Lymph nodes in the head and neck cancer: would diffusion-weighted magnetic resonance imaging solve the diagnostic dilemma?

This work aims to evaluate the diagnostic value of diffusion-weighted as a part of the magnetic resonance imaging in patients with HNC to allow...

Egyptian Journal of Radiology and Nuclear Medicine
12/01/2020
Microvascular reconstruction in head and neck cancer basis for development of an enhanced recovery protocol

The current study investigates the authors' clinical experience of head and neck cancer reconstruction for the period 2014-2016 with the aim of establishing a list of functional discharge criteria.

JPRAS Open
10/15/2020
COVID-19 screening protocols for preoperative assessment of head and neck cancer patients candidate for elective surgery in the midst of the pandemic: a narrative review with comparison between two Italian institutions

This study examined how preoperative screening had a key role in planning elective surgical activity for head and neck cancer during the COVID-19 pandemic.

Oral Oncology
01/01/2021
MEK blockade overcomes the limited activity of palbociclib in head and neck cancer.

This study investigated whether the inhibition of MEK/ERK pathway by trametinib may overcome the limited efficacy of PAL in HNC.

Translational Oncology
11/01/2020
Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients.

The purpose of this retrospective case study is to identify potential prognostic biomarkers in patients with HNSCC including APE1 , NRF2 and PPARGC1A, and SOD3 and DCN.

Oral Oncology
12/01/2020
Prognostic significance of dynamic changes in lymphocyte-to-monocyte ratio in patients with head and neck cancer treated with radiotherapy: results from a large cohort study

This study sought to investigate whether dynamic changes in lymphocyte-to-monocyte ratio occurring during the course of radiotherapy may have prognostic value in patients with HNC.

Radiotherapy and Oncology
01/01/2021
The impact of timing and modalities of dental prophylaxis on the risk of 5-fluorouracil-related oral mucositis in patients with head and neck cancer: a nationwide population-based cohort study.

This study investigated the impact of dental prophylaxis on 5-fluorouracil–related oral mucositis according to the head and neck cancer locations and treatment times.

Supportive Care in Cancer
10/19/2020
Effect of Formalin Fixation for Near-Infrared Fluorescence Imaging with an Antibody-Dye Conjugate in Head and Neck Cancer Patients.

This study evaluated the effect of formalin fixation for near-infrared fluorescence imaging of an antibody-dye complex that was intravenously administered to patients with HNSCC scheduled...

Molecular Imaging and Biology
10/19/2020
Liquid biopsy and their application progress in head and neck cancer: focus on biomarkers CTCs, cfDNA, ctDNA and EVs.

Head and neck cancer (HNC) is the sixth leading cause of death worldwide. Due to low early diagnosis rate HNC, local recurrence high distant metastasis are main reasons for treatment failure.

Biomarkers in Medicine
10/19/2020
Evaluation of patient specific care needs during treatment for head and neck cancer.

This study aimed to evaluate potential correlations between patient specific care needs, regarding...

Oral Oncology
11/01/2020
The effect of race in head and neck cancer: A meta-analysis controlling for socioeconomic status

The purpose of this study was to investigate the association between race and ethnicity and prognosis in head and neck cancers, while controlling for socioeconomic status.

American Journal of Otolaryngology
11/01/2020
Oral management strategies for radiotherapy of head and neck cancer.

The aim of this literature is to show that oral management strategy include removal infected teeth before the start of radiotherapy to prevent osteoradionecrosis, oral care for preventing...

Japanese Dental Science Review
12/01/2020
Might anxiety disorders promote head and neck cancer development

This study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma development.

IBRO Reports
12/01/2020
Number of nodal metastases and the American Joint Committee on cancer staging of head and neck cutaneous squamous cell carcinoma: A multicenter study.

This multicentre collaborative study of 1128 patients represents the largest reported cohort of patients with nodal metastases from HNcSCC.

Oral Oncology
12/01/2020
Dose volume histogram constraints in patients with head and neck cancer treated with surgery and adjuvant HDR brachytherapy: A proposal of the head and neck and skin GEC ESTRO Working group.

The HNS Working group of the GEC-ESTRO acknowledges the lack of widely accepted Dose Volume Histogram constraints in adjuvant head and neck brachytherapy and...

Radiotherapy and Oncology
01/01/2021
Notch in Head and Neck Cancer.

Head and neck cancer is a group of neoplastic diseases affecting the facial, oral, region. It one most common cancers worldwide with an aggressive, invasive evolution.

Advances in Experimental Medicine and Biology
01/01/2021
The differences of immunologic and TP53 mutant phenotypes between synchronous and metachronous head and neck cancer and esophageal cancer.

The purpose of this study is to determine the tumor genomic, immunologic expression, and risk factors of treatment outcomes for patients with double HNSCC and ESCC.

Oral Oncology
12/01/2020
Salvage surgery in head and neck cancer: External validation of predictors of disease-specific survival.

This study aimed to validate the proposal of Hamoir et al. to use three items to predict the outcomes of salvage surgery.

Oral Oncology
10/01/2020

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