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Pediatric Oncology

Pediatric Oncology

Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia

The aim of this study was evaluated the mRNA expression profile of pediatric ALL patients and the efficacy of two AURKA and AURKB designed inhibitors in a...

Scientific Reports
12/04/2020
Biomarker of Aggressive Childhood Cancer Discovered

Researchers discovered a new diagnostic marker that distinguishes a fast-growing type of the pediatric brain cancer medulloblastoma from a less-aggressive type.

Oncology Times - Latest Articles
01/05/2021
The Role of Cannabinoids as Anticancer Agents in Pediatric Oncology

This study details a comprehensive and critical review of what is known about the effects of cannabinoids on pediatric cancers...

Cancers
01/05/2021

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Physical Activity for Pediatric Cancer Survivors: A Systematic Review of Randomized Controlled Trials

This study collates evidence and evaluates the effects of physical activity interventions on physical activity level among pediatric cancer survivors who had completed active cancer treatment.

Journal of Cancer Survivorship
01/03/2021
Targeting Tumor-Associated Macrophages in the Pediatric Sarcoma Tumor Microenvironment

This review summarizes the mechanisms underlying TAM-facilitated immune evasion and tumorigenesis and discuss the potential therapeutic application of TAM-focused drugs in the...

Frontiers in Oncology
12/14/2020
Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology: A Randomized Controlled Trial Comparing Push Injections with One-Hour Infusions

This study examined children with cancer who receive vincristine chemotherapy as a one-hour infusion and compared them to children who received vincristine as a push injection.

Cancers
12/12/2020
CAR T cells for other pediatric non–B-cell hematologic malignancies

As CAR T-cell therapy has advanced in B-cell acute lymphoblastic leukemia, research is now underway to develop similar therapies for other lymphoid and myeloid malignancies for pediatric patients. 

Hematology
12/04/2020
Expression of Somatostatin Receptor Subtypes (SSTR-1–SSTR-5) in Pediatric Hematological and Oncological Disorders

This study aimed to investigate the expression of mRNA for SSTR subtypes in 15 pediatric hematological/oncological specimens by RT-PCR.

Molecules
12/07/2020
Biomarkers of cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia

Survivors of childhood acute lymphoblastic leukemia are at higher risk of developing cardiometabolic complications.

Scientific Reports
12/09/2020
Liquid Biomarkers for Pediatric Brain Tumors: Biological Features, Advantages and Perspectives

This review summarizes current knowledge on liquid biopsy markers and technologies in pediatric brain tumors, their advantages and drawbacks, as well as...

11/27/2020
Improving Pediatric Neuro-Oncology Survival Disparities in the United States–Mexico Border Region: A Cross-Border Initiative Between San Diego, California, and Tijuana, Mexico

This study prospectively assessed clinicopathologic profiles, the extent of resection, progression-free survival, and overall survival in children with CNSTs at HGT from 2010 to 2017.

JCO Global Oncology
11/20/2020
Role of implicit bias in pediatric cancer clinical trials and enrollment recommendations among pediatric oncology providers.

In the current study, the authors measured implicit bias training among pediatric oncology providers and exposure to implicit association tests. 

Cancer
10/29/2020
Candidemia in Children with Malignancies: Report from the Infection Working Group of the Hellenic Society of Pediatric Hematology-Oncology.

Candidemia is an important cause of morbidity and mortality especially in immunocompromised and hospitalized patients.

Journal of Fungi
11/10/2020
Cutaneous manifestations in pediatric oncology patients.

The objective of this study was to evaluate the cutaneous findings in pediatric oncology patients receiving chemotherapy.

Pediatric Dermatology
11/12/2020
Impact of the First Wave of COVID-19 on Pediatric Oncology and Hematology: A Report from the French Society of Pediatric Oncology.

The French society of pediatric oncology (SFCE) initiated a study to better describe COVID-19 in patients followed in French pediatric oncology and hematology wards.

Cancers
11/17/2020
Association between in-line filtration and Type I hypersensitivity reactions in pediatric oncology patients receiving intravenous etoposide.

The objective of this study was to describe hypersensitivity reactions with and without the use of in-line filters during intravenous etoposide therapy in pediatric oncology patients.

Pediatric Hematology and Oncology
11/05/2020
Commonly Reported Adverse Events Associated With Pediatric Immunotherapy: A Systematic Review From the Children's Oncology Group.

The purpose of this systematic review was to review available evidence to: (a) identify commonly reported AEs associated with immunotherapy agents frequently used in...

Journal of Pediatric Oncology Nursing
10/28/2020
Nurse-initiated protocols in the emergency department management of pediatric oncology patients with fever and suspected neutropenia: a scoping review protocol.

This study provides an overview of the existing evidence regarding nurse-initiated protocols in the emergency department management of pediatric oncology patients...

JBI evidence synthesis
11/04/2020
Implications of Tumor Characteristics and Treatment Modality on Local Recurrence and Functional Outcomes in Children with Chest Wall Sarcoma: A Pediatric Surgical Oncology Research Collaborative Study.

Children with chest wall sarcoma require multimodal therapy including chemotherapy, surgery and/or radiation.

Annals of Surgery
11/04/2020
Towards homogenization of total body irradiation practices in pediatric patients across SIOPE affiliated centers a survey by the SIOPE radiation oncology working group.

The study purpose was to evaluate clinical practices regarding TBI, such as fractionation, organ shielding and delivery techniques, among SIOPE affiliated radiotherapy centers.

Radiotherapy and Oncology
10/30/2020
Changes in hair cortisol and self-reported stress measures following mindfulness-based stress reduction (MBSR): A proof-of-concept study in pediatric hematology-oncology professionals

Little data is available on the effect of mindfulness amongst pediatric hematology-oncology professionals.

Complementary Therapies in Clinical Practice
10/23/2020
Emerging hyperthermia applications for pediatric oncology

This review summarizes the state of current applications of hyperthermia in pediatric oncology and discusses the use of hyperthermia in the context of other available treatments and promising pre-c

Advanced Drug Delivery Reviews
10/24/2020
Custom Pediatric Oncology NGS Panel Identifies Somatic Mosaicism in Archival Tissue and Enhances Targeted Clinical Care

Disorders in the PIK3CA-related overgrowth spectrum due to somatic mosaicism are associated with segmental overgrowth of the body in conjunction with vascular, skeletal...

Pediatric Neurology
10/01/2020
Pediatric CNS Tumor Patients Have Significantly Lower Requirement of Tissue Plasminogen Activator for Episodes of Central Venous Catheter Dysfunction Compared With Other Pediatric Oncology Patients: Results of a Population-based Cohort Study.

The goal of this study was to investigate the CVC experience and use of tPA for episodes of CVC dysfunction in pediatric patients with CNS tumors in comparison with other patients.

Journal of Pediatric Hematology Oncology
10/01/2020
Platelet transfusion practice and platelet refractoriness for a cohort of pediatric oncology patients: A single-center study.

Platelet transfusions are an essential aspect of supportive care for pediatric oncology patients.

Pediatric Blood &amp
09/25/2020
Evaluation of Inflammatory Biomarkers in Pediatric Hematology-Oncology Patients With Bloodstream Infection.

Bloodstream infection is a serious complication in pediatric hematology-oncology patients.

Journal of Pediatric Hematology Oncology
09/15/2020
Incorporating Absolute Phagocyte Count With Absolute Neutrophil Count as a Measure for Safe Discharge for Pediatric Oncology Febrile Neutropenia: A Pilot Study.

Adequate bone marrow recovery is a discharge requirement after admission for febrile neutropenia in oncology patients, without specific threshold in consensus guidelines.

Journal of Pediatric Hematology Oncology
10/15/2020
Socialization of Coping in Pediatric Oncology Settings: Theoretical Consideration on Parent-Child Connections in Posttraumatic Growth.

This theoretical article aims to summarize the results of studies relevant parental influence on coping with childhood cancer and provide implications for future research focused...

Frontiers in Psychology
09/18/2020
Relationship-centered communication training for pediatric hematology/oncology providers to improve patient experience

This study evaluates the efficacy of this intervention to improve patient/family experience in healthcare encounters.

Authorea Preprints
10/13/2020
Coping and Social Adjustment in Pediatric Oncology: From Diagnosis to 12 Months.

This study investigated the association between coping with cancer-related stress and problems in social adjustment across the first year after a pediatric cancer diagnosis.

Journal of Pediatric Psychology
09/15/2020
Much is left unspoken: Self-reports from families in pediatric oncology.

The aim of this study was to explore how families in pediatric oncology experienced illness‐related information and communication with professionals and within the family.

Pediatric Blood &amp
09/25/2020
Current challenges facing pediatric radiation oncology viewed through an economics lens.

Because cancer in children is relatively infrequent and the role of pediatric RT is limited, there are a small number of cases of children requiring RT in the US compared to the number of...

Pediatric Blood &amp
09/29/2020
Impact of a Best Practice Prevention Bundle on Central Line-associated Bloodstream Infection (CLABSI) Rates and Outcomes in Pediatric Hematology, Oncology, and Hematopoietic Cell Transplantation Patients in Inpatient and Ambulatory Settings.

The authors sought to evaluate the influence of a standardized best practice CVC maintenance bundle on the burden of and risk factors for...

Journal of Pediatric Hematology Oncology
09/21/2020
Validating an opioid prescribing algorithm in post-operative pediatric surgical oncology patients

The authors of this study developed an algorithm to decrease opioid prescriptions for pediatric oncology patients at discharge following surgery, based on a retrospective analysis to...

Journal of Pediatric Surgery
10/06/2020
Development of an Integrative Care Program in a Pediatric Oncology Unit.

This article describes what needs be considered in implementing care practices, in this case an integrative care program consisting of anthroposophic treatments, in an ICU of a teaching hospital.

Complementary Medicine Research
10/09/2020
Subcutaneous Analgesic System versus Epidural for Post-Operative Pain Control in Surgical Pediatric Oncology Patients

A surgeon-placed subcutaneous analgesic system may be able to provide equivalent pain control epidural analgesia for pediatric oncology patients undergoing open operations with...

Journal of Pediatric Surgery
10/06/2020
Pharmacogenomics in Pediatric Oncology: Mitigating Adverse Drug Reactions While Preserving Efficacy

Cancer is the leading cause of death in American children older than year age.

Annual Review of Pharmacology and Toxicology
01/06/2021
Guidance for Pediatric Hematology-Oncology (PHO) and Hematopoietic Stem Cell Transplant Services during COVID-19 Pandemic: A Consensus Statement by PHO Chapter of Indian Academy of Pediatrics

With the recent Pandemic of Covid-19 affecting more than 180 countries across the globe, services to children with blood disorders and cancers are likely to be affected.

09/01/2020

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