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International Journal of Molecular Sciences

International Journal of Molecular Sciences
Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer

This study discusses the molecular epidemiology of the main druggable genetic alterations in non-small cell lung cancer, namely EGFR, KRAS, BRAF, MET, and HER2 mutations...

International Journal of Molecular Sciences
01/09/2021
Exploring the Potential of Drug Response Assays for Precision Medicine in Ovarian Cancer

This review highlights several drug-response assays developed in ovarian cancer and discussed the current challenges and future prospects of these assays in the...

International Journal of Molecular Sciences
12/30/2020
Melatonin as an Oncostatic Molecule Based on its Anti-Aromatase Role in Breast Cancer

This review summarizes the inhibitory role of melatonin in aromatase action, suggesting its role as a possible oncostatic molecule in breast cancer.

International Journal of Molecular Sciences
01/04/2021
CHID1 Is a Novel Prognostic Marker of Non-Small Cell Lung Cancer

This study evaluates immune cells markers in 100 NSCLC specimens. Immunohistochemical analysis reveals no prognostic value for the markers studied, except CD163 and CD206.

International Journal of Molecular Sciences
01/05/2021
Infections and Immunotherapy in Lung Cancer: A Bad Relationship?

This analysis aims to review the current evidence in order to clarify the complex correlation between infections and lung cancer.

International Journal of Molecular Sciences
12/22/2020
PI3K/AKT/mTOR Signaling Pathway in Breast Cancer: From Molecular Landscape to Clinical Aspects

The main purpose of this review is to present general aspects of breast cancer, the components of the AKT signaling pathway, the factors that activate...

International Journal of Molecular Sciences
12/26/2020
Spatio-Temporal Bone Remodeling after Hematopoietic Stem Cell Transplantation

The interaction of hematopoietic cells and the bone microenvironment to maintain bone homeostasis is increasingly appreciated.

International Journal of Molecular Sciences
12/29/2020
Circulating Exosomal miRNAs as Biomarkers for the Diagnosis and Prognosis of Colorectal Cancer

This study reports the potential of circulating exosomal miRNAs to act as biomarkers for the diagnosis and prognosis of CRC.

International Journal of Molecular Sciences
12/31/2020
Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer

Study investigators review the clinical value and novel biological roles of LOX family members in tumor progression and the TME of liver cancers.

International Journal of Molecular Sciences
12/21/2020
Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer

This study investigates the function of microphthalmia-associated transcription factor, which contributes to the development of melanoma, in epithelial ovarian cancer. 

International Journal of Molecular Sciences
12/21/2020
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