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Cancer Therapy Advisor

Cancer Therapy Advisor
Men at Increased Risk for Mortality Following Allogeneic Hematopoietic Stem Cell Transplant

GVHD and age at transplant were significantly associated with mortality risk.

Cancer Therapy Advisor
12/05/2020
Durable Responses Seen With Odronextamab in Refractory B-Cell NHLs

Odronextamab, demonstrated promising antitumor activity and an acceptable safety profile — including with cytokine release syndrome (CRS)–mitigating strategies — among patients with B-cell NHLs.

Cancer Therapy Advisor
12/07/2020
High False-Negative RT-PCR Rates for SARS-CoV-2 Observed in Patients With Hematologic Malignancies

Hematologic malignancy was associated with more severe COVID-19 and high false-negative SARS-CoV-2 rates as measured by standard RT-PCR testing...

Cancer Therapy Advisor
12/06/2020
BCMA-Directed CAR-T Therapy Shows Clinical Activity in Multiple Myeloma

An investigational CAR-T therapy that targets B-cell maturation antigen showed clinical activity in heavily pretreated patients with relapsed/refractory multiple myeloma...

Cancer Therapy Advisor
12/07/2020
G-CSF Pretreatment Ameliorates the Activity of an Autologous DC-Based Vaccine in Melanoma

Pretreatment with granulocyte colony stimulating factor failed to improve dendritic cell collection for an autologous DC-based vaccine for advanced, resectable melanoma...

Cancer Therapy Advisor
11/13/2020
DLL3-Targeted BiTE Shows Antitumor Activity in SCLC

An anti-DLL3 bispecific T-cell engager demonstrated antitumor activity with an acceptable safety profile, according to interim results of a phase 1 study presented at the virtual... 

Cancer Therapy Advisor
11/13/2020
More NSCLC Downstaging With Neoadjuvant Chemotherapy Plus ICI

Neoadjuvant chemotherapy plus nivolumab resulted in a higher frequency of disease downstaging and lower frequency of upstaging compared with other therapies among patients with...

Cancer Therapy Advisor
11/12/2020
Pseudoprogression With Immunotherapy in Cervical Cancer

Pseudoprogression with ICIs was observed in a cohort of patients with recurrent cervical cancer, including early, delayed, and serial events, according to the results of a study presented at the...

Cancer Therapy Advisor
11/12/2020
Fostering Trust Between Parents of Children With Cancer and Physicians
Cancer Therapy Advisor
FDA: Efficacy, Safety Concerns With Breast Cancer Combo Therapy
Cancer Therapy Advisor
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