Scientific Reports

Scientific Reports
Evaluation of Wavelength Ranges and Tissue Depth Probed by Diffuse Reflectance Spectroscopy for Colorectal Cancer Detection

Investigators evaluate the diagnostic capabilities of diffuse reflectance spectroscopy for CRC detection by building 6 classification models based on support vector machines.

Scientific Reports
Targeted Sequencing to Identify Genetic Alterations and Prognostic Markers in Pediatric T-Cell Acute Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia is caused by the accumulation of multiple genetic alterations.

Scientific Reports
Preceding Endoscopic Submucosal Dissection in Submucosal Invasive Gastric Cancer Patients Does Not Impact Clinical Outcomes

This study aims to evaluate the specific influence of endoscopic submucosal dissection on the prognosis of patients with T1b2 gastric cancer.

Scientific Reports
Non-Invasive Skin Sampling of Tryptophan/Kynurenine Ratio in Vitro Towards a Skin Cancer Biomarker

Non-invasive topical sampling of Trp/Kyn can therefore serve as a promising concept for skin cancer diagnostics.

Scientific Reports
A Pre-Operative Prognostic Score for the Selection of Patients for Salvage Surgery After Recurrent Head and Neck Squamous Cell Carcinomas

The present study is a single-center retrospective analysis of 164 patients treated with salvage surgery after recurrence of head and neck cancer.

Scientific Reports
A Novel Immune Prognostic Index for Stratification of High-Risk Patients With Early Breast Cancer

Using public gene expression microarray datasets, study investigators classify breast cancer patients into three risk groups according to clinical risk and proliferation risk.

Scientific Reports
Deciphering the Complex Circulating Immune Cell Microenvironment in Chronic Lymphocytic Leukaemia Using Patient Similarity Networks

This study reveals high inter-individual heterogeneity in the distribution and activation of bystander immune cells in CLL, depending on the bulk of the CLL cells.

Scientific Reports
Engineering a Reporter Cell Line to Mimic the High Oligomannose Presenting Surface Immunoglobulin of Follicular Lymphoma B Cells

From deep sequencing of the variable heavy and light chain sequences of follicular lymphoma involved tissue sections, this study identified the consensus variable sequences possessing...

Scientific Reports
Feasibility of Reduced-Dose Posttransplant Cyclophosphamide and Cotransplantation of Peripheral Blood Stem Cells and Umbilical Cord-Derived Mesenchymal Stem Cells for SAA

Posttransplant cyclophosphamide as GVHD prophylaxis is an effective strategie for patients receiving MSD-HSCT and haplo-HSCT.

Scientific Reports
Defining Eligible Patients for Allele-Selective Chemotherapies Targeting NAT2 in Colorectal Cancer

This study recently identified a subset of CRC patients who are heterozygous for a wild-type and a low activity allele but lack the wild-type allele in their tumors due to loss of...

Scientific Reports
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