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Targeting Chromatin Complexes in Myeloid Malignancies and Beyond: From Basic Mechanisms to Clinical Innovation

This review summarizes some of the current concepts on the role epigenetic modifiers in malignant chromatin states with a specific focus on myeloid malignancies and...

Cells
12/21/2020
NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma, which is common and lethal.

Cells
12/12/2020
Chronic Lymphocytic Leukemia-Induced Humoral Immunosuppression: A Systematic Review

The aim of the study was to review the available literature data on patients with CLL, with particular regard to the pathogenesis of the disease and the impact of...

Cells
11/02/2020
Molecular Mechanisms of Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia: Ongoing Challenges and Future Treatments

Treatment of FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD)-positive acute myeloid leukemia remains a challenge despite the development of novel FLT3-directed...

Cells
11/17/2020
Update on Circulating Tumor Cells in Genitourinary Tumors with Focus on Prostate Cancer.

Current developments in the treatment of genitourinary tumors underline unmet clinical need for biomarkers to improve decision-making a challenging setting.

Cells
06/19/2020
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