Frontiers in Oncology

Frontiers in Oncology
Connexins in Lung Cancer and Brain Metastasis

This review discusses junctional or non-junctional hemichannel studies in lung cancer development and brain metastasis, highlighting important unanswered questions...

Frontiers in Oncology
Artificial Intelligence in Medical Imaging and Its Application in Sonography for the Management of Liver Tumor

This study summarizes AI development in medical images with challenges to task setting, data curation, and focus on the application of AI for the managements of liver tumor...

Frontiers in Oncology
FLT3 Mutations in Acute Myeloid Leukemia: Key Concepts and Emerging Controversies

The FLT3 receptor is overexpressed on the majority of acute myeloid leukemia blasts.

Frontiers in Oncology
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype

This study reviews recent progress in understanding the development of breast cancer during pregnancy and their unique subtype of triple negative which is the...

Frontiers in Oncology
Dyspnea in Patients Receiving Radical Radiotherapy for Non-Small Cell Lung Cancer

This study investigates the relationship between dose-volume parameters and subjective changes in dyspnea as a measure of RILI and the relationship to spirometry.

Frontiers in Oncology
Alpha Thalassemia/Intellectual Disability X-Linked Deficiency Sensitizes Non-Small Cell Lung Cancer to Immune Checkpoint Inhibitors

The immune checkpoint inhibitors have achieved great success in the treatment of NSCLC patients. However, the response rate is low.

Frontiers in Oncology
Mitochondrial Bioenergetics at the Onset of Drug Resistance in Hematological Malignancies

In hematological malignancies, there is a strong relationship between cellular metabolism, mitochondrial bioenergetics, interconnections with supportive microenvironment and drug resistance.

Frontiers in Oncology
Hematopoeitic Cell Transplantation and CAR T-Cell Therapy: Complements or Competitors?

The advent of both technologies revolutionized treatment of many hematologic malignancies, both offering the chance at sustained remissions for patients who would otherwise...

Frontiers in Oncology
Targeting Tumor-Associated Macrophages in the Pediatric Sarcoma Tumor Microenvironment

This review summarizes the mechanisms underlying TAM-facilitated immune evasion and tumorigenesis and discuss the potential therapeutic application of TAM-focused drugs in the...

Frontiers in Oncology
Acute Myeloid Leukemia: From Biology to Clinical Practices Through Development and Pre-Clinical Therapeutics

Insight into Leukemia stem cells and assessment of cell surface markers have enabled characterization of LSCs from hematopoietic stem and progenitor cells.

Frontiers in Oncology
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