Chronic ITP

Chronic ITP

New findings suggest that patients with cancer who have non-O blood types (types A, B, and AB) have a higher risk of developing VTEs at 3 months or more after their initial cancer diagnosis. 


Study investigators report a case of refractory ITP in which changes in platelet-related markers with therapeutic agents are worthy of the attention of clinicians.


Researchers shared retrospective data of patients with chronic ITP and associations with autoimmune dysregulation in parents and primary immunodeficiency disorders.

Oncology Learning Network

B cells play a central role in the pathogenesis of ITP by participating in humoral immunity. The aim of the research is to provide a potential approach in the management of ITP.

Stem Cells International

In this study, investigators report the qualitative and quantitative profiles of the ITP proteome.

Cancer Cell International

A finding of thrombocytosis was associated with a greatly increased risk for some cancers up to 5 years later.


According to study results presented during ESMO Congress 2021, corticosteroids appeared to have a benefit in the treatment of mild to moderate CT-induced thrombocytopenia...

Hematology Advisor

Among patients with cancer, COVID-19 infection may lead to life-threatening thromboembolic events even after acute illness, necessitating risk prediction tools for TEs.

Hematology Advisor

Due to its property of increasing platelet counts, vincristine is also used to treat patients with immune thrombocytopenia. 


In this study, investigators analyze the effect of decitabine on T-cell subpopulations in ITP in vitro and in vivo.


In this study, investigators compare the efficiency and toxicities of splenectomy and eltrombopag as second-line treatments in ITP.


The data suggest that earlier treatment with romiplostim may help children to avoid the side effects associated with corticosteroid use and reduce the need for subsequent treatment.


This study attempts to elucidate the correlation between endothelial dysfunction and disease severity of ITP and find related markers to predict response to low-dose decitabine treatment.

Frontiers in Immunology

This review discusses platelet clearance and production, especially the role of the anti-GPIbα antibody and desialylation in the pathophysiology of ITP and therapy for this disease.

Experimental Hematology & Oncology

This work is to further clarify the relationship between T cell immune dysfunction and the pathogenesis of ITP.

International Journal of General Medicine

Beyond the inhibition of the autoimmune response, new TPO-RAs that stimulate platelet production have been developed.

Journal of Clinical Medicine

Misdiagnosed primary ITP in children is rare in the international prospective Pediatric and Adult Registry on Chronic ITP.

Blood Advances

The study examines the prevalence of H. pylori among chronic ITP children and to investigate the impact of treatment of H. pylori infection on platelet count response.


Prolonged thrombocytopenia occurs in up to 37% of patients after HSCT and is associated with adverse prognosis and increased risk of bleeding.


Presented here is a case of a 14-year-old female diagnosed with immune thrombocytopenia.


TTP is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.

Journal of Clinical Medicine

This study examines the phenotypes of lymphocytes in ITP to clarify whether they predict outcomes after the discontinuation of eltrombopag.


The purpose of this study is to compare the clinical efficacy of laparoscopic splenectomy and open splenectomy in the treatment of Idiopathic thrombocytopenic purpura.


The optimal approach to managing children newly diagnosed with this disease remains controversial.

MedPage Today

The aim of this study is to describe the use of primary anti-infective prophylaxis in common clinical practice in patients affected by ITP and treated with RTX. 

Annals of Hematology

Study investigators review the newer approaches in the treatment of ITP.

Journal of Community Hospital Internal Medicine Perspectives

This study found that the expression of the immunoproteasome catalytic subunit, LMP2, was significantly upregulated in peripheral blood mononuclear cells of active ITP patients...

Frontiers in Immunology

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