X

Chronic ITP

Chronic ITP

New findings suggest that patients with cancer who have non-O blood types (types A, B, and AB) have a higher risk of developing VTEs at 3 months or more after their initial cancer diagnosis. 

Medscape
04/27/2022

Study investigators report a case of refractory ITP in which changes in platelet-related markers with therapeutic agents are worthy of the attention of clinicians.

Medicine
01/14/2022

Researchers shared retrospective data of patients with chronic ITP and associations with autoimmune dysregulation in parents and primary immunodeficiency disorders.

Oncology Learning Network
12/21/2021

B cells play a central role in the pathogenesis of ITP by participating in humoral immunity. The aim of the research is to provide a potential approach in the management of ITP.

Stem Cells International
11/08/2021

In this study, investigators report the qualitative and quantitative profiles of the ITP proteome.

Cancer Cell International
10/18/2021

A finding of thrombocytosis was associated with a greatly increased risk for some cancers up to 5 years later.

Medscape
10/04/2021

According to study results presented during ESMO Congress 2021, corticosteroids appeared to have a benefit in the treatment of mild to moderate CT-induced thrombocytopenia...

Hematology Advisor
09/20/2021

Among patients with cancer, COVID-19 infection may lead to life-threatening thromboembolic events even after acute illness, necessitating risk prediction tools for TEs.

Hematology Advisor
09/18/2021

Due to its property of increasing platelet counts, vincristine is also used to treat patients with immune thrombocytopenia. 

Molecules
09/02/2021

In this study, investigators analyze the effect of decitabine on T-cell subpopulations in ITP in vitro and in vivo.

Blood
08/26/2021

In this study, investigators compare the efficiency and toxicities of splenectomy and eltrombopag as second-line treatments in ITP.

08/25/2021

The data suggest that earlier treatment with romiplostim may help children to avoid the side effects associated with corticosteroid use and reduce the need for subsequent treatment.

07/26/2021

This study attempts to elucidate the correlation between endothelial dysfunction and disease severity of ITP and find related markers to predict response to low-dose decitabine treatment.

Frontiers in Immunology
07/13/2021

This review discusses platelet clearance and production, especially the role of the anti-GPIbα antibody and desialylation in the pathophysiology of ITP and therapy for this disease.

Experimental Hematology & Oncology
03/15/2021

This work is to further clarify the relationship between T cell immune dysfunction and the pathogenesis of ITP.

International Journal of General Medicine
03/18/2021

Beyond the inhibition of the autoimmune response, new TPO-RAs that stimulate platelet production have been developed.

Journal of Clinical Medicine
03/02/2021

Misdiagnosed primary ITP in children is rare in the international prospective Pediatric and Adult Registry on Chronic ITP.

Blood Advances
03/12/2021

The study examines the prevalence of H. pylori among chronic ITP children and to investigate the impact of treatment of H. pylori infection on platelet count response.

02/08/2021

Prolonged thrombocytopenia occurs in up to 37% of patients after HSCT and is associated with adverse prognosis and increased risk of bleeding.

02/06/2021

Presented here is a case of a 14-year-old female diagnosed with immune thrombocytopenia.

02/02/2021

TTP is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.

Journal of Clinical Medicine
02/02/2021

This study examines the phenotypes of lymphocytes in ITP to clarify whether they predict outcomes after the discontinuation of eltrombopag.

02/02/2021

The purpose of this study is to compare the clinical efficacy of laparoscopic splenectomy and open splenectomy in the treatment of Idiopathic thrombocytopenic purpura.

01/29/2021

The optimal approach to managing children newly diagnosed with this disease remains controversial.

MedPage Today

The aim of this study is to describe the use of primary anti-infective prophylaxis in common clinical practice in patients affected by ITP and treated with RTX. 

Annals of Hematology
01/26/2021

Study investigators review the newer approaches in the treatment of ITP.

Journal of Community Hospital Internal Medicine Perspectives
01/26/2021

This study found that the expression of the immunoproteasome catalytic subunit, LMP2, was significantly upregulated in peripheral blood mononuclear cells of active ITP patients...

Frontiers in Immunology
01/20/2021

source list reference

RGB(78, 191, 50)
rgb(171, 222, 222)
#7d60d9
rgb(219, 18, 118)
#2694a4
#32a887
200, 66, 245
#85eb24
rgb(80,199,199)
rgb(195, 2, 230)
rgb (247, 7, 79)
#352625
#4d4537
rgb(14, 133, 237)
rgb(80,199,199)
rgb(252, 3, 223)
rgb (132, 101, 173)
rgb(209, 15, 15)
rgb(115, 43, 196)
rgb(9, 151, 227)
RGB(171, 29, 196)
rgb(252, 186, 3)
#d2093c
#8e3f1c
rgb(242, 0, 137)
rgb (247, 7, 79)
#76b6c3
rgb(48, 38, 189)
rgb(231, 165, 240)
rgb(230, 21, 49)
rgb (132, 101, 173)
#bfcfc8
rgb (252, 186, 3)
#c61417
rgb(156, 242, 7)
rgb(91, 128, 189)
rgb(247, 139, 109)
#67e25b
#efef71
rgb (132, 101, 173)
rgb(181, 112, 164)
#03cffc
rgb(224, 4, 129)
#42fc9a
rgb(20, 13, 222)
rgb(84, 54, 94)
rgb(80, 147, 199)
rgb(117, 2, 247)
rgb(153, 146, 129)
rgb(11, 160, 224)
#cc529a
#c59445
rgb(245, 111, 66)
#c8cc0c
#bf6be3
rgb (245, 152, 2)
rgb(164, 116, 173)
rgb(219, 105, 96)
rgb(11, 160, 224)
#e8085a
rgb(66, 135, 245)
#97d1a0
rgb(101, 11, 212)
#74e391
#eb6342
#b61f77
rgb(169, 196, 201)
#a153ac
rgb(125, 127, 130)
rgb(5, 235, 235)
#e7f6e3
#6fc969
#9a8c2c
#a9c507
rgb(235, 190, 9)
#2b9ab3
#e61923
rgb(209, 227, 11)
#990677
#4a7bab
200, 66, 245
rgb (191, 171, 145)
#89f67c
#49a21d
rgb(126, 14, 237)
rbg(167, 124, 235)
rgb (132, 101, 173)
rgb((217, 11, 193)
#2c990a
rbg(16, 162, 230)
rgb(110, 57, 65)
#d7da81
#f5ce42
rgb(80,199,199)
rgb(217, 7, 192)
#575662
rgb (247, 7, 79)
rgb(107, 129, 201)
rgb (214, 104, 96)
rgb(224, 224, 4)
#a60538
rgb(2, 230, 230)
rgb(186, 130, 237)
rgb(235, 64, 52)
#49cde9
rgb(214, 139, 202)
rgb (132, 101, 173)
rgb(10, 191, 137)
#c20fce
rgb(80,199,199)
#d95d39
#eb5834