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Febrile Neutropenia

Febrile Neutropenia

Loss of ATF4 Leads to Functional Aging-like Attrition of Adult Hematopoietic Stem Cells

Investigators report that ATF4 deficiency provokes severe hematopoietic stem cells defects with multifaceted aging-like phenotype via cell-autonomous mechanisms.

Science Advances
12/22/2021
A Prediction Model for Bacteremia and Transfer to Intensive Care in Pediatric and Adolescent Cancer Patients With Febrile Neutropenia

This study's goal was to develop a model for predicting blood stream infection and transfer to intensive care at time of presentation in pediatric cancer patients with FN.

12/14/2021
Efficacy and Cost of G-CSF Derivatives for Prophylaxis of Febrile Neutropenia in Lymphoma and Multiple Myeloma Patients Underwent Autologous HSCT

This study compared the efficacies and costs between pegfilgrastim and filgrastim prophylaxis for febrile neutropenia post-ASCT for lymphoma and multiple myeloma patients.

Hematology
12/14/2021

Adding Venetoclax to DA-EPOCH-R Leads to Excess Deaths in Double-Hit Lymphoma

Adding venetoclax to chemoimmunotherapy results in excess treatment-related deaths in patients with double-hit lymphoma, a phase 2/3 trial suggests.

Cancer Therapy Advisor
12/13/2021
Deep Learning Computer-Aided Detection System for Pneumonia in Febrile Neutropenia Patients

Investigators evaluated the performance of a deep learning-based CAD system in pneumonia detection in the CXRs of consecutive patients and investigated...

BMC Pulmonary Medicine
12/07/2021
Important to Control for FN Risks During Comparative Effectiveness Analyses of Breast Cancer, NHL

Patients with NHL or breast cancer with intermediate risk for febrile neutropenia maintain that risk even with pegfilgrastim prophylaxis, according to research...

Oncology Learning Network
03/19/2021
Decision-Tree Derivation and External Validation of a New Clinical Decision Rule to Predict the Risk of Severe Infection During Febrile Neutropenia in Children Treated for Cancer

This study aimed to build and validate a new CDR (DISCERN-FN) to predict the risk of severe infection in children with febrile neutropenia.

The Lancet Child &amp
12/03/2021
Determining Disease Through White Blood Cells

Neutrophils makeup 45-75% of white cells in the circulation, and are the major first-line defense against infectious pathogens such as bacteria and some fungi.

12/07/2021
FDA Rejects Novel Agent for Chemo-induced Neutropenia

The novel agent plinabulin has not been approved by the FDA, as the agency recently announced that more clinical data is need.

Medscape
12/02/2021

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