RET+ Advanced Thyroid Cancer

RET+ Advanced Thyroid Cancer

Association of Genetic Alterations With Disease Characteristics and Response to Treatment in Pediatric Differentiated Thyroid Cancer

RET and NTRK fusions were common somatic genetic alterations in pediatric patients with thyroid cancer and were associated with an increased risk of metastasis and poorer treatment outcome.

The ASCO Post
Recurrence of Papillary Thyroid Cancer Predicted by Genetic Risk Model

Analysis of mRNA, miRNA, and protein-encoding genes may predict the chance of recurrent papillary thyroid cancer at the first occurrence of disease. 

Cancer Therapy Advisor
Anxiety During the COVID-19 Pandemic: A Web-Based Survey of Thyroid Cancer Survivors

Doctors determine the effects of the pandemic on thyroid cancer survivors’ healthcare interactions and quality of life.

Endocrine Practice

Dabrafenib Plus Trametinib in Patients With BRAF V600E–Mutant Anaplastic Thyroid Cancer

Scientists describe the efficacy and safety of dabrafenib plus trametinib in the full ROAR ATC cohort of 36 patients with approximately 4 years of additional study follow-up.

Annals of Oncology
Age Cutoff of 14 Years May Be More Suitable Than 18 Years for Pediatric Thyroid Cancer

A pediatric cutoff age of 15 for differentiated thyroid cancer care may be more appropriate than the American Thyroid Association’s cutoff of 18 due to risk factors related to survival rates. 

Diagnostic Efficacy of Ultrasound, Cytology, and BRAFV600E Mutation Analysis and Their Combined Use in Thyroid Nodule Screening for Papillary Thyroid Microcarcinoma

This study evaluates the diagnostic efficiency of the three methods and their combined use in screening for papillary thyroid microcarcinoma.

Frontiers in Oncology
Head-to-Head Comparison of 68Ga-PSMA-11 and 131I in the Follow-Up of Well-Differentiated Metastatic Thyroid Cancer

Scientists assess whether this novel image method possesses applicability in thyroid neoplasms follow up, for diagnostic and potentially therapeutic purposes.

Frontiers in Endocrinology
Vitamin D Insufficiency Predicts Susceptibility of Parathyroid Hormone Reduction after Total Thyroidectomy in Thyroid Cancer Patients

Researchers evaluate the potential effect of preoperative vitamin D level on postoperative hypoparathyroidism in a large consecutive group of patients who underwent TT for PTC.

International Journal of Endocrinology
Apatinib Improves PFS, OS in Radioactive Iodine-Refractory Thyroid Cancer

Apatinib improved survival outcomes, compared with placebo, in patients with radioactive iodine-refractory differentiated thyroid cancer, according to new trial results. 

Cancer Therapy Advisor
Metabolic Syndrome Links With Increased Thyroid Cancer Incidence

Metabolic Syndrome and its individual conditions, abdominal obesity, low levels of HDL cholesterol, and elevated blood pressure, appear likely to contribute to the development of thyroid cancer.

International Medullary Thyroid Carcinoma Grading System: Detecting Adverse Outcomes

In a study reported in the Journal of Clinical Oncology, authors developed a two-tiered international medullary thyroid carcinoma grading system that identifies...

The ASCO Post
Air Pollution May Be Linked to Increased Occurrence of Thyroid Cancer

According to results from a nested case-control study, exposure to meteorological conditions, including air pollution, may affect the occurrence of thyroid cancer.

Oncology Learning Network
Pralsetinib Shows Promise in Patients With RET-Altered Thyroid Cancer

According to findings from phase 1/2 of the ARROW trial, pralsetinib shows promise as a potent, well-tolerated treatment for patients with RET-altered thyroid cancer.

Oncology Learning Network
SLCO4A1 is a Prognosis-Associated Biomarker Involved in Neutrophil-Mediated Immunity in Thyroid Cancer

The study aimed to investigate the value of solute carrier organic anion transporter family member 4A1 in thyroid cancer mainly from three aspects: expression, prognosis, and...

Pesticide Exposure Linked to Increased Risk for Thyroid Cancer

According to an investigation done on male pesticide applicators, exposure to pesticides such as metalaxyl and lindane was associated with an increased risk for thyroid cancer. 

Oncology Learning Network

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