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SABCS 2021: Updates in HER2 Low

SABCS 2021: Updates in HER2 Low

Therapy Switch Based on Mutation May Prolong PFS in Breast Cancer

Switching therapy based on early biomarker results increased PFS in patients with HR+, HER2- metastatic breast cancer according to new findings presented at SABCS.

Medscape
12/14/2021
Palbociclib Regimens Extend Survival for Black, Hispanic Women With Advanced Breast Cancer

The addition of palbociclib to endocrine therapy prolonged survival for Black and Hispanic women with HR+, HER2- metastatic breast cancer, according to results presented at SABCS 2021.

Healio
12/16/2021
PALLAS Trial: Addition of Adjuvant Palbociclib to Endocrine Therapy in Early HR-Positive, HER2-Negative Breast Cancer

The final analysis of the phase III PALLAS trial has shown no invasive DFS benefit with the addition of adjuvant palbociclib to endocrine therapy in patients with HR+, HER2-negative...

The ASCO Post
12/08/2021

ctDNA Promising Biomarker in Ribociclib, Letrozole-Treated HR+/HER2- Advanced Breast Cancer

The presence of detectable mutation in a baseline liquid biopsy appeared to be a negative prognostic factor for women with HR+/HER2-advanced breast cancer treated with first-line...

Cancer Therapy Advisor
12/09/2021
Genomic-Based Targeted Therapy Improved PFS for Certain Metastatic Breast Cancers

Patients with metastatic breast cancer had improved outcomes with the use of multigene sequencing as a therapeutic decision tool when identified genomic alterations...

Cancer Therapy Advisor
12/08/2021
Elacestrant Improved PFS in Metastatic Breast Cancer Progressing on CDK4/6 Therapy

Elacestrant demonstrated significant and clinically meaningful improvement in PFS compared with standard of care endocrine therapy in men and postmenopausal women with ER+/HER2- mBC...

Cancer Therapy Advisor
12/08/2021
Molecular Tumor Profiling May Improve Treatment Matching for Patients With Metastatic Breast Cancer

Multigene sequencing and SNP array as a therapeutic decision tool improved the outcomes of patients with metastatic breast cancer if the patients carried alterations classified...

The ASCO Post
12/07/2021
Greenwich LifeSciences Announces Acceptance of Two Posters at Upcoming 2021 SABCS Breast Cancer Conference

Greenwich LifeSciences, Inc. (Nasdaq: GLSI) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of GLSI-100, an immunotherapy to prevent breast cancer recurrences in patients who have previously undergone surgery, today announced that two abstracts and posters have been accepted for presentation at the upcoming SABCS.

11/11/2021
CDK4/6 Inhibitors Combined With Fulvestrant for Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer: FDA Analysis of Overall Survival

Dr Jennifer Gao and colleagues found the addition of CDK4/6 inhibitor treatment to fulvestrant resulted in a consistent OS benefit vs placebo plus fulvestrant in patients with HR+.

The ASCO Post
11/09/2021
Daiichi Sankyo to Present New Breast Cancer Data Across DXd ADC Portfolio at 2021 SABCS

MUNICH & BASKING RIDGE, N.J.--(BUSINESS WIRE)--Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) will present new breast cancer research data across its DXd ADC portfolio at the 2021 San Antonio Breast Cancer Symposium (#SABCS21) to be held December 7 to 10, 2021.

12/01/2021

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