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Head And Neck Cancer

Head And Neck Cancer

New Database of HPV-Negative Head & Neck Carcinomas Unveiled

New research clarifies the contributions of genes, proteins, and signaling pathways associated with HPV-negative head and neck squamous cell carcinomas.

Oncology Times - Latest Articles
04/05/2021
Tipifarnib for Patients With Advanced HRAS-Mutant Head and Neck Cancer and High Variant Allele Frequency

In a phase II trial, Ho et al finds that tipifarnib produces a high response rate among patients with recurrent or metastatic HNSCC with HRAS mutations and high variant allele frequency.

The ASCO Post
04/05/2021
Cetuximab, Docetaxel, and Cisplatin versus Platinum, Fluorouracil, and Cetuximab as First-Line Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

Results from a phase 2 trial of the TPEx chemotherapy regimen show promising results, with a median overall survival of 14·0 months in first-line recurrent or metastatic HNSCC.

The Lancet Oncology
04/01/2021

Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy

This prospective randomized open-label trial evaluates the role of acupuncture in the treatment of pain related to curative and adjuvant (chemo)radiotherapy of head and neck cancer.

Journal of Clinical Medicine
03/07/2021
Electrochemotherapy in the Treatment of Head and Neck Cancer: Current Conditions and Future Directions

This review describes current knowledge and data on the use of ECT in various forms of HNCs across different clinical settings, with attention to future clinical and research perspectives.

Cancers
03/19/2021
Single-Cell Deconvolution of Head and Neck Squamous Cell Carcinoma

This study finds that higher proportions of a class of immune cells (tumor-infiltrating regulatory T-cells) are associated with improved survival in head and neck cancer. 

Cancers
03/11/2021
The Role of Anti-EGFR Agents in the Era of Immunotherapy

This review focuses on the current role of anti-EGFR therapies in HNCs, underlying available clinical data and mechanisms of resistance, and highlight future perspectives regarding...

Therapeutic Advances in Medical Oncology
03/09/2021
A Principal Component of Quality of Life Measures Is Associated with Survival for Head and Neck Cancer Patients Treated with Radiation Therapy

The relationship between post-treatment recovery of HRQOL and outcome in head and neck cancer is not well characterized. 

Cancers
03/08/2021
Immune-Related Mutational Landscape and Gene Signatures: Prognostic Value and Therapeutic Impact for Head and Neck Cancer

This review summarizes more recent efforts to elucidate immune-related mutational landscapes and gene expression signatures by integrative analysis of multi-omics data...

Cancers
03/08/2021
Identification of Four Key Prognostic Genes and Three Potential Drugs in Human Papillomavirus Negative Head and Neck Squamous Cell Carcinoma

This study examines the identification of biomarkers for HPV-positive and HPV-negative HNSCCs.

Cancer Cell International
03/12/2021
The Hidden Curve Behind COVID-19 Outbreak: The Impact of Delay in Treatment Initiation in Cancer Patients and How to Mitigate the Additional Risk of Dying—The Head and Neck Cancer Model

Study investigators analyze the impact on global cancer mortality considering the decline in oncology care during the COVID-19 outbreak using head and neck cancer as a model.

03/11/2021
FGF19/FGFR4 Signaling Axis Confines and Switches the Role of Melatonin in Head and Neck Cancer Metastasis

As there is no consensus about the effective dosages of melatonin in cancer management, it is imperative to fully understand the dose-dependent responsiveness of cancer cells...

03/10/2021
Perioperative Mortality of Head and Neck Cancers

Most clinical studies of head and neck cancers focus on the prognosis of patients with head and neck cancer, but perioperative mortality is rarely mentioned.

BMC Cancer
03/09/2021
Precision Medicine Approaches to Overcome Resistance to Therapy in Head and Neck Cancers

This review outlines the mechanisms of resistance to the therapeutic strategies currently used in HNSCC, discusses combination treatment strategies to overcome them, and...

Frontiers in Oncology
02/25/2021
Taking a Step Down on the Reconstruction Ladder for Head and Neck Reconstruction During the COVID-19 Pandemic

The objective of this study is to share the experience and approach towards head and neck reconstruction during the COVID-19 pandemic in Pakistan.

BMC Surgery
03/08/2021
Aurora Kinases Shed Light on Resistance to EGFR Inhibition in Head and Neck Cancer

Joo-leng and colleagues examine acquired resistance to gefitinib, an EGFR-tyrosine kinase inhibitor in multiple EGFR wild-type HNSCC cell lines.

02/24/2021
A Bioadhesive Barrier-Forming Oral Liquid Gel Improved Oral Mucositis and Nutritional Status in Patients With Head and Neck Cancers Undergoing Radiotherapy

This study observes the effects of Episil® on the OM and nutritional status of patients with head and neck cancers undergoing RT.

Frontiers in Oncology
02/22/2021
Monocarboxylate Transporter-1 (MCT1) Protein Expression in Head and Neck Cancer Affects Clinical Outcome

Treatment of locally advanced, unresectable head and neck squamous cell carcinoma often yields only modest results with radiochemotherapy as standard of care.

Scientific Reports
02/25/2021
Osteopontin Levels in Patients with Squamous Metastatic Head and Neck Cancer

The aim of this study is to determine OPN levels in patients with HNSCC of different primary locations and to assess its prognostic significance in metastasis development.

Medicina
02/21/2021
The Overall Efficacy and Outcomes of Metronomic Tegafur-Uracil Chemotherapy on Locally Advanced Head and Neck Squamous Cell Carcinoma

In this retrospective study, study investigators examine the outcomes of metronomic chemotherapy with tegafur–uracil in locally advanced HNSCC.

02/23/2021
PRF1 is a Prognostic Marker and Correlated With Immune Infiltration in Head and Neck Squamous Cell Carcinoma

This study researches the correlations of PRF1 with clinical prognosis and tumor immune infiltration in head and neck squamous cell carcinoma.

Translational Oncology
02/20/2021
Deep Learning in Head and Neck Tumor Multiomics Diagnosis and Analysis

Study investigators review multiomics image analysis of head and neck tumors using CNN and other DL neural networks.

Frontiers in Genetics
02/10/2021
Novel Diagnostic Approaches for Assessment of the Clinically Negative Neck in Head and Neck Cancer Patients

This review discusses the potential of several innovative diagnostic approaches to guide customized management of the clinically negative neck in head and neck cancer patients.

Frontiers in Oncology
02/05/2021
The Incidence of Myocardial Infarction and Stroke in Head and Neck Cancer Patients

This study analyzes the incidence and risks of myocardial infarction and stroke by cancer site and treatment modality in 22,737 patients newly diagnosed with HNC registered...

Scientific Reports
02/18/2021
Oral and Ocular Late Effects in Head and Neck Cancer Patients Treated With Radiotherapy

This study demonstrates that HNC patients treated with IMRT experience late effects in terms of xerostomia and ocular dryness underlining the importance of interdisciplinary approach...

Scientific Reports
02/17/2021
Integrated Analysis Reveals ENDOU as a Biomarker in Head and Neck Squamous Cell Carcinoma Progression

This study identifies genes with clinical significance by integrated bioinformatics analysis and investigate their function in HNSCC.

Frontiers in Oncology
02/05/2021
The Prospective Evaluation and Risk Factors of Dysphagia After Surgery in Patients With Oral Cancer

This prospective study investigates the change of swallowing ability using the Swallowing Ability Scale System and swallowing-related QOL by PSS-H&N.

01/25/2021
Successful Use of Nivolumab in a Patient with Head and Neck Cancer After Allogeneic Bone Marrow Transplantation

Recently, programmed cell death 1(PD-1) inhibitors have shown a significant curative effect in the treatment of most solid cancers and some hematological malignancies.

OncoTargets and Therapy
02/10/2021
Integrated Analysis of Deregulation microRNA Expression in Head and Neck Squamous Cell Carcinoma

This study analyzes the eccentrically expressed miRNAs in HNSCC tissues based on the miRNA-Seq data of HNSCC patients available in the Cancer Genome Atlas database.

02/12/2021
Radiotherapy and Immunotherapy for Head and Neck Cancer: Current Evidence and Challenges

This review describes the current preclinical and clinical evidence for radioimmunotherapy, with a particular focus on studies directly relevant to head and neck squamous cell carcinoma...

Frontiers in Oncology
02/03/2021
The Effects of Early Nutritional Intervention on Oral Mucositis and Nutritional Status of Patients With Head and Neck Cancer Treated With Radiotherapy

This review summarizes the possible pathogenesis of RIOM, commonly used assessment tools for malnutrition in patients, and recent studies on the effects of early...

Frontiers in Oncology
02/01/2021
Identification of Three Autophagy-Related Long Non-Coding RNAs as a Novel Head and Neck Squamous Cell Carcinoma Prognostic Signature

In the present study, HNSCC RNA sequences and autophagy-related gene data were extracted from The Cancer Genome Atlas database and the Human Autophagy Database.

Frontiers in Oncology
01/26/2021
Bioelectrical Impedance Analysis in Patients Undergoing Major Head and Neck Surgery

This study aims to investigate perioperative changes in patients undergoing major head and neck surgery and to examine the impact of perioperative fluid administration on...

02/02/2021
HPV Meets APOBEC: New Players in Head and Neck Cancer

This review focuses on recent advances on the role of APOBEC proteins in HPV-positive vs. HPV-negative HNSCC.

International Journal of Molecular Sciences
01/30/2021
Ubiquitin Carboxyl-Terminal Hydrolases and Human Malignancies: The Novel Prognostic and Therapeutic Implications for Head and Neck Cancer

This review summarizes the physiological and pathological functions of the UCHs family, which provides enlightenment of potential mechanisms of UCHs family in HNC pathogenesis...

Frontiers in Oncology
01/29/2021
Overexpressed PLAU and its Potential Prognostic Value in Head and Neck Squamous Cell Carcinoma

Metastasis is a major event for survival and prognosis in patients with head and neck squamous cell carcinomas.

01/15/2021
Predictive Impact of C-Reactive Protein to Albumin Ratio for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Receiving Nivolumab

This study aims to analyze the clinical usability of the CAR in comparison with that of the NLR.

Scientific Reports
02/02/2021
Stimuli-Responsive Drug Delivery Systems for Head and Neck Cancer Therapy

In this article, recent studies on stimuli-responsive DDSs for HNC therapy are summarized.

01/27/2021
Treatment Outcomes of Patients with Head and Neck Squamous Cell Carcinoma of Unknown Primary

The purpose of this study is to evaluate clinical characteristics and treatment outcomes of patients with head and neck squamous cell carcinoma of unknown primary.

01/25/2021
Presence of Human Papillomavirus and Epstein–Barr Virus, but Absence of Merkel Cell Polyomavirus, in Head and Neck Cancer of Non-Smokers and Non-Drinkers

This study determines the presence and prognostic value of HPV, EBV, MCPyV, and cell cycle proteins in HNSCC of non-smokers and non-drinkers.

Frontiers in Oncology
01/20/2021
Impact of Geniohyoid and Masseter Muscle Masses on Dysphagia After Salvage Surgery and Radiotherapy in Head and Neck Cancer

This study aims to determine whether geniohyoid and/or masseter muscle mass can predict the severity of dysphagia after salvage surgery for head and neck cancer.

Scientific Reports
01/26/2021
The Roles of Extracellular Vesicles in the Development, Microenvironment, Anticancer Drug Resistance, and Therapy of Head and Neck Squamous Cell Carcinoma

The clinical application of EVS in HNSCC is assessed in this study.

01/21/2021
Depression, Anxiety, Fatigue, and Quality of Life in a Large Sample of Patients Suffering from Head and Neck Cancer in Comparison With the General Population

This study aims to compare depression, anxiety, fatigue and QoL between HNC patients and a large sample of the general population in Germany and to examine...

BMC Cancer
01/22/2021
Hypothyroidism and Risks of Cerebrovascular Complications Among Patients With Head and Neck Cancer After Radiotherapy

Hypothyroidism and carotid artery stenosis are complications of radiotherapy in patients with head and neck cancer. 

01/19/2021
Recent Advances and Future Directions in Clinical Management of Head and Neck Squamous Cell Carcinoma

This article reviews historical data to provide a context and highlights recent data in understanding of epidemiology and pathophysiology and supporting changes in treatments of HNSCC...

Cancers
01/18/2021
Prediction of Response in Head and Neck Tumor: Focus on Main Hot Topics in Research

This paper discusses those markers specific for evaluate response to radiation therapy in head and neck cancer for a shift toward a biological personalization of radiotherapy.

Frontiers in Oncology
01/08/2021
Reinforcing the Known Hygiene Practices for the Health Care Workers Along with Working Guidelines for Managing Head and Neck Cancer Patients in the COVID Era

Treatment for patients with cancer needs to be delivered despite the existing pandemic. This puts the health care workers at a higher risk to contract infection.

01/07/2021
Roles of the Wnt Signaling Pathway in Head and Neck Squamous Cell Carcinoma

This paper summarizes the groundbreaking discoveries and recent advances involving the Wnt signaling pathway and highlight the relevance of this pathway in head & neck squamous cell cancer.

01/05/2021
Risk Factors for Osteoradionecrosis of the Jaw in Patients with Head and Neck Squamous Cell Carcinoma

This study evaluates factors associated with ORNJ in patients with HNSCC, focusing on jaw-related dose–volume histogram parameters.

01/05/2021
Comparison of Intrafractional Motion in Head and Neck Cancer Between Two Immobilization Methods During Stereotactic Ablative Radiation Therapy by CyberKnife

Maintaining immobilization to minimize spine motion is very important during salvage stereotactic ablative radiation therapy for recurrent head and neck cancer.

01/05/2021
A Pre-Operative Prognostic Score for the Selection of Patients for Salvage Surgery After Recurrent Head and Neck Squamous Cell Carcinomas

The present study is a single-center retrospective analysis of 164 patients treated with salvage surgery after recurrence of head and neck cancer.

Scientific Reports
01/12/2021
Diagnostic and Prognostic Value of FOXD1 Expression in Head and Neck Squamous Cell Carcinoma

FOXD1 was significantly upregulated in HNSCC and was a good diagnostic biomarker and an independent predictor of poor survival and low rate of recurrence-free survival...

01/01/2021
Postoperative Radiotherapy is Associated With Improved Survival in pT1-2N1 Oral and Oropharyngeal Cancer Without Adequate Neck Dissection

This study assesses the benefit of postoperative radiotherapy in patients with pT1-2N1M0 oral and oropharyngeal cancer by the quality of neck dissection.

01/06/2021
Imaging of Head and Neck Mucosa-Associated Lymphoid Tissue Lymphoma (MALToma)

The aim of this article is to illustrate the varied radiological and clinical features of MALToma in the head and neck.

01/12/2021
Endoscopic Surveillance for Metachronous Esophageal Squamous Cell Neoplasms among Head and Neck Cancer Patients

This study recommends image enhanced endoscopy including Lugol chromoendoscopy as the screening tool for incident HNSCC patients.

Cancers
12/18/2020
Prehabilitation in Head and Neck Cancer Patients

Dysphagia is one consequence of head and neck cancer that has a significant impact on quality of life for head and neck cancer survivors.

01/06/2021
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Landscape of natural killer cell activity in head and neck squamous cell carcinoma

This study reviews the activity of NK cells in HNSCC, paying special attention to the role of environmental and genetic determinants of NK cell antitumor function.

12/21/2020
Research progress of radiation-induced hypothyroidism in head and neck cancer

This paper reviews the factors related to hypothyroidism after radiotherapy in patients with head and neck cancer to facilitate the prevention of radiation-induced hypothyroidism and...

01/01/2021
Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

The identification and validation of strategies to individualize therapy of patients with head and neck squamous cell carcinoma require cellular and animal models that accurately represent...

Cancers
12/12/2020
NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma, which is common and lethal.

Cells
12/12/2020
Molecular margins in head and neck cancer: Current techniques and future directions

Complete tumor extirpation with clear surgical margins remains a central tenet of oncologic head and neck surgery.

Oral Oncology
11/01/2020
Impact of treatment delay due to the pandemic of COVID-19 on the efficacy of immunotherapy in head and neck cancer patients

This study retrospectively analyzed 24 HNC patients treated with immune checkpoint inhibitors in our cancer institute prior to the outbreak of COVID-19 who were re-evaluated after...

12/11/2020
Radiomic features based on Hessian index for prediction of prognosis in head-and-neck cancer patients

This study demonstrated the usefulness of radiomic features based on the Hessian index of differential topology for the prediction of prognosis prior to treatment in HNC patients.

Scientific Reports
12/04/2020
Comprehensive Geriatric Assessment: A Case Report on Personalizing Cancer Care of an Older Adult Patient With Head and Neck Cancer.

This article aims to present comprehensive geriatric as an approach to personalizing care for older adults with cancer. 

Clinical Journal of Oncology Nursing
10/01/2020
Vitamin D in Head and Neck Cancer: a Systematic Review

This systematic literature review aimed to determine whether vitamin D deficiency is related to head and neck cancer etiology and outcome.

11/20/2020
Photoacoustic and Magnetic Resonance Imaging of Hybrid Manganese Dioxide-Coated Ultra-Small NaGdF4 Nanoparticles for Spatiotemporal Modulation of Hypoxia in Head and Neck Cancer

Tumor hypoxia is a documented negative prognostic factor that contributes to treatment resistance in head and neck cancer.

Cancers
11/06/2020
Toxicity syndrome and early competing deaths in head-and-neck cancer undergoing radiation therapy: Observation and hypothesis.

Radiotherapy and/or CRT is the mainstay for treatment of LAHNC. Sepsis remains a poorly understood and unrecognized event in cancer.

Medical Hypotheses
10/01/2020
STAT3 as a predictive biomarker in head and neck cancer: A validation study.

LAHNSCC treatment consists of radiotherapy (RT) alone or CCRT. CCRT is accompanied by substantially more toxicity than RT alone.

Pathology Research and Practice
11/01/2020
Institution-Specific Strategies for Head and Neck Oncology Triage During the COVID-19 Pandemic

This work seeks to better understand the triage strategies employed by head and neck oncologic surgical divisions during the initial phases of the COVID-19 outbreak.

12/04/2020
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

The independent effects of smoking and alcohol in head and neck cancer are not clear, given the strong association between these risk factors.

11/27/2020
The Clinical Significance of Dickkopf Wnt Signaling Pathway Inhibitor Gene Family in Head and Neck Squamous Cell Carcinoma

This study analyzed the expression of different DKK family members in patients with HNSCC and the relationships between their expression and clinical parameters, using...

11/26/2020
Extracellular Vesicles in Head and Neck Cancer: A Potential New Trend in Diagnosis, Prognosis, and Treatment

This study discussed the functionality of EVs in HNCs and their clinical potential with regards to biomarker and therapeutic capabilities.

International Journal of Molecular Sciences
11/04/2020
Awareness of Human Papillomavirus and Its Oncogenic Potential in Head and Neck Cancer among Students: Still More Questions than Answers

In the past years, HPV has been proved to be an important risk factor for HNSCCs, especially in the oropharynx.

International Journal of Environmental Research and Public Health
11/22/2020
Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis

This meta-analysis examined the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with HNC.

10/22/2020
Challenges in diagnosing head and neck cancer in primary health care.

The low incidence of HNC renders its detection challenging for a general practitioner in primary health care.

Annals of Medicine
01/01/2021
Prognostic significance of dynamic changes in lymphocyte-to-monocyte ratio in patients with head and neck cancer treated with radiotherapy: results from a large cohort study

This study sought to investigate whether dynamic changes in lymphocyte-to-monocyte ratio occurring during the course of RT may have prognostic value in patients with HNC.

Radiotherapy and Oncology
01/01/2021
Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients.

The purpose of this retrospective case study is to identify potential prognostic biomarkers in patients with HNSCC including APE1...

Oral Oncology
12/01/2020
Using the Glasgow Benefit Inventory questionnaire to quantify the health benefits of lymphoedema treatment in patients with head and neck cancer

The aim of this study was to quantify the health benefits of lymphoedema treatment using the Glasgow Inventory Benefit questionnaire, in patients with a history of treated head and neck cancer.

Applied Cancer Research
12/01/2020
Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19

The impact of COVID-19 on patients with cancer is emerging, but data are urgently needed for HNC patients or survivors who are inherently high-risk for severe illness and...

Oral Oncology
11/06/2020
Association of Immigration Status and Chinese and South Asian Ethnicity With Incidence of Head and Neck Cancer.

This study separates the independent associations of ethnicity and immigration with HNC incidence and identifies certain high-risk ethnocultural groups.

Archives of Otolaryngology-head &amp
11/05/2020
Electronic Cigarettes and Head and Neck Cancer Risk—Current State of Art

This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer.

Cancers
11/05/2020
State Medicaid expansion status, insurance coverage and stage at diagnosis in head and neck cancer patients.

This study aimed to quantify associations between state Medicaid expansions and changes in insurance coverage rates and stage at diagnosis of HNC.

Oral Oncology
11/01/2020
p53-dependent glutamine usage determines susceptibility to oxidative stress in radioresistant head and neck cancer cells.

Thus, p53 status may be an important biomarker for selecting cancer treatment strategies, including metabolic drugs and ROS-inducing agents, for recurrent cancers after...

Cellular Signalling
01/01/2021
Lymph nodes in the head and neck cancer: would diffusion-weighted magnetic resonance imaging solve the diagnostic dilemma?

This work aims to evaluate the diagnostic value of diffusion-weighted as a part of the magnetic resonance imaging in patients with HNC to allow...

Egyptian Journal of Radiology and Nuclear Medicine
12/01/2020
Microvascular reconstruction in head and neck cancer basis for development of an enhanced recovery protocol

The current study investigates the authors' clinical experience of head and neck cancer reconstruction for the period 2014-2016 with the aim of establishing a list of functional discharge criteria.

JPRAS Open
10/15/2020
COVID-19 screening protocols for preoperative assessment of head and neck cancer patients candidate for elective surgery in the midst of the pandemic: a narrative review with comparison between two Italian institutions

This study examined how preoperative screening had a key role in planning elective surgical activity for head and neck cancer during the COVID-19 pandemic.

Oral Oncology
01/01/2021
MEK blockade overcomes the limited activity of palbociclib in head and neck cancer.

This study investigated whether the inhibition of MEK/ERK pathway by trametinib may overcome the limited efficacy of PAL in HNC.

Translational Oncology
11/01/2020
Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients.

The purpose of this retrospective case study is to identify potential prognostic biomarkers in patients with HNSCC including APE1 , NRF2 and PPARGC1A, and SOD3 and DCN.

Oral Oncology
12/01/2020
Prognostic significance of dynamic changes in lymphocyte-to-monocyte ratio in patients with head and neck cancer treated with radiotherapy: results from a large cohort study

This study sought to investigate whether dynamic changes in lymphocyte-to-monocyte ratio occurring during the course of radiotherapy may have prognostic value in patients with HNC.

Radiotherapy and Oncology
01/01/2021
The impact of timing and modalities of dental prophylaxis on the risk of 5-fluorouracil-related oral mucositis in patients with head and neck cancer: a nationwide population-based cohort study.

This study investigated the impact of dental prophylaxis on 5-fluorouracil–related oral mucositis according to the head and neck cancer locations and treatment times.

Supportive Care in Cancer
10/19/2020
Effect of Formalin Fixation for Near-Infrared Fluorescence Imaging with an Antibody-Dye Conjugate in Head and Neck Cancer Patients.

This study evaluated the effect of formalin fixation for near-infrared fluorescence imaging of an antibody-dye complex that was intravenously administered to patients with HNSCC scheduled...

Molecular Imaging and Biology
10/19/2020
Liquid biopsy and their application progress in head and neck cancer: focus on biomarkers CTCs, cfDNA, ctDNA and EVs.

Head and neck cancer (HNC) is the sixth leading cause of death worldwide. Due to low early diagnosis rate HNC, local recurrence high distant metastasis are main reasons for treatment failure.

Biomarkers in Medicine
10/19/2020
Evaluation of patient specific care needs during treatment for head and neck cancer.

This study aimed to evaluate potential correlations between patient specific care needs, regarding...

Oral Oncology
11/01/2020
The effect of race in head and neck cancer: A meta-analysis controlling for socioeconomic status

The purpose of this study was to investigate the association between race and ethnicity and prognosis in head and neck cancers, while controlling for socioeconomic status.

American Journal of Otolaryngology
11/01/2020
Oral management strategies for radiotherapy of head and neck cancer.

The aim of this literature is to show that oral management strategy include removal infected teeth before the start of radiotherapy to prevent osteoradionecrosis, oral care for preventing...

Japanese Dental Science Review
12/01/2020
Might anxiety disorders promote head and neck cancer development

This study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma development.

IBRO Reports
12/01/2020
Number of nodal metastases and the American Joint Committee on cancer staging of head and neck cutaneous squamous cell carcinoma: A multicenter study.

This multicentre collaborative study of 1128 patients represents the largest reported cohort of patients with nodal metastases from HNcSCC.

Oral Oncology
12/01/2020
Dose volume histogram constraints in patients with head and neck cancer treated with surgery and adjuvant HDR brachytherapy: A proposal of the head and neck and skin GEC ESTRO Working group.

The HNS Working group of the GEC-ESTRO acknowledges the lack of widely accepted Dose Volume Histogram constraints in adjuvant head and neck brachytherapy and...

Radiotherapy and Oncology
01/01/2021
Notch in Head and Neck Cancer.

Head and neck cancer is a group of neoplastic diseases affecting the facial, oral, region. It one most common cancers worldwide with an aggressive, invasive evolution.

Advances in Experimental Medicine and Biology
01/01/2021
The differences of immunologic and TP53 mutant phenotypes between synchronous and metachronous head and neck cancer and esophageal cancer.

The purpose of this study is to determine the tumor genomic, immunologic expression, and risk factors of treatment outcomes for patients with double HNSCC and ESCC.

Oral Oncology
12/01/2020
Salvage surgery in head and neck cancer: External validation of predictors of disease-specific survival.

This study aimed to validate the proposal of Hamoir et al. to use three items to predict the outcomes of salvage surgery.

Oral Oncology
10/01/2020

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