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An artificial intelligence (AI) tool helps doctors predict the cancer risk in lung nodules seen on CT, according to a new study published in the journal Radiology.

Medical Xpress
05/24/2022

Researchers in Australia found higher rates of melanoma diagnosis, particularly in situ melanoma, and skin biopsies among people who had undergone skin screenings. 

Oncology Nurse Advisor
05/26/2022

This hybrid effectiveness-implementation study will evaluate the effectiveness and implementation of an mHealth intervention consisting of interactive text-messages, electronic tools, and... 

BMC Health Services Research
05/23/2022

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Content Feed

Our results support the analysis of cfDNA as a promising strategy for performing molecular characterization, detection of chromosomal aberrations and monitoring of patients with MDS.

Blood Advances
05/23/2022

To characterize the experiences of providers in completing the cause of death section on death certificates, with particular reference to deaths in people who have cancer.

PLOS ONE
05/20/2022

We conducted an updated meta-analysis with stringent inclusion criteria to ensure homogeneous studies to determine the effect of ER subtypes on ovarian cancer prognosis.

Journal of Ovarian Research
05/24/2022

Using PDX and ex vivo explants from estrogen receptor (ER) positive, ER mutant and TNBC patients, we further demonstrated that CB effectively blocks therapy-sensitive and therapy-resistant...

Communications Biology
05/24/2022

This hybrid effectiveness-implementation study will evaluate the effectiveness and implementation of an mHealth intervention consisting of interactive text-messages, electronic tools, and... 

BMC Health Services Research
05/23/2022

Although adolescents and young adults (AYAs) who survive leukemia are living much longer than ever before, their life spans are still shorter than those of the general population, a new study concl

Medscape
05/20/2022

More extensive surgery does not improve survival over less aggressive surgery in younger women with breast cancer, according to data presented at the 2022 American Society of...

The ASCO Post
05/25/2022

Here we report a cancer vaccine that induces a coordinated attack by diverse T cell and natural killer (NK) cell populations. 

Nature
05/25/2022

Herein, we assessed the clinicopathological characteristics and long-term surgical outcomes of gastric NEC and MiNEN patients in our hospital.

World Journal of Surgical Oncology
05/24/2022

In this week’s edition, Dr Brian Van Tine, a professor of Medicine and Pediatrics at Washington University in St. Louis, shares headlines for updates in colorectal cancer, mantle cell lymphoma, and renal cell carcinoma. View the transcript here.

05/26/2022

A reinduction therapy approach using mitoxantrone with clofarabine was shown to be safe and well tolerated at the recommended phase 2 dose for clofarabine. 

Cancer Therapy Advisor
05/24/2022

CDKN2A/B deletion is associated with distinct characteristics and serves as a poor prognostic factor in pediatric ALL, especially in TP53 deletion carriers.

Frontiers in Oncology
05/24/2022

The CART, known as 7CAR8 and recently described in a paper in the journal Blood, is highly active against T-cell acute lymphoblastic leukemia (T-ALL) in multiple preclinical models.

Medical Xpress
05/23/2022

Here we identify oxidative phosphorylation (OxPhos) as a critical pathway for leukemia cell survival and demonstrate a direct relationship between NOTCH1, elevated OxPhos gene expression...

Nature Communications
05/19/2022

New software developed by Peter Mac and collaborators is helping patients diagnosed with acute lymphoblastic leukemia (ALL) to determine what subtype they have.

Medical Xpress
05/19/2022

Use of multiple immune pathway inhibitors appears to be superior to checkpoint inhibitor therapy alone as neoadjuvant therapy for resectable non–small cell lung cancer (NSCLC)...

The ASCO Post
05/25/2022

To investigate the efficacy and safety of lung stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC) including oligorecurrent and oligoprogressive disease.

Frontiers in Oncology
05/24/2022

We report post hoc efficacy outcomes in patients with and without brain metastases at baseline, and present data on the incidence and management of CNS adverse events (AEs) in CROWN.

Journal of Clinical Oncology
05/23/2022

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

Medical Xpress
05/23/2022

We investigated the predictive value of TAM infiltration in patients with non-small cell lung cancer (NSCLC) treated with ICBs and characterized their transcriptomic profiles.

Journal for ImmunoTherapy of Cancer
05/20/2022

Patients who identify as a sexual minority are less likely than heterosexual patients to undergo cervical cancer screening, according to a study published in Cancer.

Cancer Therapy Advisor
05/24/2022

Time-restricted eating (TRE), limiting energy intake to eight hours followed by fasting for 16 hours (16:8 TRE), is associated with a reduction in cardiovascular disease (CVD) risk...

Oncology Nurse Advisor
05/25/2022

An artificial intelligence (AI) tool helps doctors predict the cancer risk in lung nodules seen on CT, according to a new study published in the journal Radiology.

Medical Xpress
05/24/2022

This study assesses patient navigator team member perspectives regarding implementation barriers and facilitators one year post-study implementation.

BMC Health Services Research
05/21/2022

 These methods provide an approach for pan-solid tumor comprehensive genomic profiling with high analytical performance. 

Nature Communications
05/20/2022

This year's theme will be Advancing Equitable Cancer Care Through Innovation, with more than 200 sessions offering resources and research on this topic.

Oncology Times - Latest Articles
05/20/2022

This study aims to clarify the mechanistic action of long non-coding RNA (lncRNA) SNHG12 in the development of renal cell carcinoma, which may be associated with...

Cancer Cell International
05/21/2022

The purpose of this study was to evaluate the bactericidal efficacy of OLG in gastrointestinal cancer surgery.

BMC Surgery
05/19/2022

In this study, we introduced the C3aR domain into a CAR and generated BB-ζ-C3aR CAR-T targeting CD19 or BCMA.

Journal of Hematology & Oncology
05/21/2022

This randomized pilot trial assessed the feasibility and acceptability of a 6 to 7 week supported self-management intervention (Prepare to Care) offering psychoeducation and...

Integrative Cancer Therapies
05/16/2022

Researchers found the addition of metformin to standard breast cancer treatments did not improve outcomes in the two most common types of breast cancer, hormone receptor-positive or negative. 

Medical Xpress
05/24/2022

Our data with respect to alterations in the levels of soluble immune checkpoints are seemingly consistent with the existence of significant, systemic immune dysregulation...

Frontiers in Immunology
05/23/2022

There is a need for identification of novel markers that can be used at the time of diagnosis for predicting clinical outcomes, especially for early-stage and late recurrence.

PLOS ONE
05/23/2022

We seek to carry out an isobaric label based proteomic experiment to delineate protein signatures that can accurately reflect the metastatic state of the sentinel lymph nodes in early breast cancer

Scientific Reports
05/22/2022

Prognosis is better evaluated by PAM50 ROR in early-stage HR + /HER2- breast cancer and significantly differs among intrinsic subtypes. 

BMC Cancer
05/14/2022

Exploring the repertoire of peptides presented on major histocompatibility complexes (MHC) has been utilized to identify targets for immunotherapy in many hematological malignancies.

Blood Advances
05/13/2022

A triplet regimen consisting of the PARP (poly [ADP-ribose] polymerase) inhibitor olaparib, metronomic (the chronic administration of low, equally spaced doses of) cyclophosphamide, and...

The ASCO Post
05/24/2022

Young stroke patients have an increased risk of being diagnosed with a new cancer in the years following their stroke, a new study shows.

Medscape
05/13/2022

Here, we show a correlation of ILK expression with the immunosuppressive TME and cancer prognosis.

Frontiers in Oncology
05/25/2022

In this pilot study, we performed proton nuclear magnetic resonance spectroscopy (1H-NMR) on 29 cases of FL and 11 control patient specimens.

Scientific Reports
05/18/2022

The aim of the present study was to create up-to-date reference values for mPC patients and compare these to POLO data and general population norm data. 

BMC Cancer
05/20/2022

We sought to determine whether STAT3 induces the expression of GLI1 in neoplastic MF fibrocytes and whether STAT3-activated GLI1 plays a role in the induction of BM fibrosis.

Cell Death & Disease
05/20/2022

The present study aimed to analyze and thematically organize a large amount of feedback from patients who had been treated for cancer within the last 6 months.

BMC Health Services Research
05/23/2022

These results establish key technical considerations for the implementation of cWGTS as an integrated test in clinical oncology.

Nature Communications
05/18/2022

PMBC mortality for higher educated Asian women is elevated in comparison to their counterparts with less education. 

PLOS ONE
05/18/2022

Herein, we apply integrative transcriptome analysis to discover a new exosome biomarker for the diagnosis of ovarian carcinoma.

Discover Oncology
05/16/2022

Using data from a large prospective cohort study of patients with an advanced cancer, we aimed to assess the number and predictors of aggressive interventions during last month of life...

BMC Palliative Care
05/16/2022

We retrospectively retrieved urine cytology slides and matched histological results. High-power field panel images were annotated by a certified urological pathologist. 

Frontiers in Oncology
05/24/2022

This retrospective study herein aims to compare and analyze the data from patients identified as HGBL and non-HGBL based on FISH analysis and to define valuable diagnostic predictors...

Frontiers in Immunology
05/24/2022

We investigated the prognostic significance of CLS in a cohort of 69 trastuzumab-naïve and 117 adjuvant trastuzumab-treated patients with primary HER2 + breast cancer.

Scientific Reports
05/24/2022