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A Multi-Modal, Physician-Centered Intervention to Improve Guideline-Concordant Prostate Cancer Imaging

Research describes and analyzes the implementation of the PCIS intervention to determine the effect of a physician-focused behavioral intervention on VHA prostate cancer imaging use. 

Trials
10/18/2021
Association Analyses of TP53 Mutation With Prognosis, Tumor Mutational Burden, and Immunological Features in Acute Myeloid Leukemia

Somatic mutations in AML patients were found using The Cancer Genome Atlas dataset and BeatAML dataset and then researchers identified the common mutant genes in the two cohorts. 

Frontiers in Immunology
10/21/2021
Prognostic Value of Immune-Related lncRNA Pairs in Patients With Bladder Cancer

Research establishes a novel model to predict the efficacy of immunotherapy regardless of expression.

World Journal of Surgical Oncology
10/18/2021

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Content Feed

Prognostic Value of Immune-Related lncRNA Pairs in Patients With Bladder Cancer

Research establishes a novel model to predict the efficacy of immunotherapy regardless of expression.

World Journal of Surgical Oncology
10/18/2021
Extended Letrozole Prolonged Survival in Postmenopausal Patients With Breast Cancer

When compared with the standard 2-3 years of letrozole, 5 years of letrozole treatment improved both disease-free survival and overall survival.

Cancer Therapy Advisor
10/18/2021
M6A Associated TSUC7 Inhibition Contributed to Erlotinib Resistance in Lung Adenocarcinoma Through a Notch Signaling Activation Dependent Way

 Researchers tentatively explored the supporting role of TUSC7 in cancer suppression, trying to establish the m6A correlated lncRNA functions in modulating the TKIs therapies resistance.

Journal of Experimental & Clinical Cancer Research
10/16/2021
Hsp90 Up-Regulates PD-L1 to Promote HPV-Positive Cervical Cancer via HER2/PI3K/AKT Pathway

The therapeutic effect of heat shock protein 90 knockdown on HPV16+ cervical cancer progression and the underlying mechanism is investigated.

Molecular Medicine
10/19/2021
Replication Catastrophe is Responsible for Intrinsic PAR Glycohydrolase Inhibitor-Sensitivity in Patient-Derived Ovarian Cancer Models

Scientists explore the use of a transcript-based biomarker, and provide insight into the design of future clinical trials of PARGi in patients with ovarian cancer.

Journal of Experimental & Clinical Cancer Research
10/16/2021
Incidence of Suicide Among Adolescent and Young Adult Cancer Patients

As the survival rates of cancer patients continue to increase, most cancer patients now die of non-cancer causes, this study characterizes suicide mortality among AYA patients in the US...

Cancer Cell International
10/18/2021
Effects and Prognostic Values of miR-30c-5p Target Genes in Gastric Cancer via a Comprehensive Analysis Using Bioinformatics

Potential diagnostic and prognostic values of miR-30c-5p target genes in gastric cancer by using a filtration step analysis and integrated bioinformatics tools are explored.

Scientific Reports
10/18/2021
Extracorporeal Photopheresis in Pediatric Chronic Graft vs Host Disease

ECP is a safe treatment approach for kids who have steroid-refractory cGVHD, while enabling high response rates but with further immunosuppressive treatment required for some patients.

Hematology Advisor
10/20/2021
Combined Immune Score Predicts the Prognosis of Newly Diagnosed Multiple Myeloma Patients in the Bortezomib-Based Therapy Era

This study investigated the effect of a combined immune score including the lymphocyte-to-monocyte ratio and uninvolved immunoglobulin levels on the prognosis of newly diagnosed multiple myeloma...

Medicine
10/15/2021
Younger Age at Diagnosis May Predict Higher VTE Risk in Patients With Multiple Myeloma

Among younger patients with multiple myeloma and those with a high white cell count, higher-intensity thromboprophylaxis may be necessary for reducing the risk of venous thromboembolism.

Cancer Therapy Advisor
10/14/2021
A Sigh of Relief: Vaccine-Associated Hypermetabolic Lymphadenopathy Following the Third COVID-19 Vaccine Dose is Short in Duration and Uncommonly Interferes With the Interpretation of [18F]FDG PET-CT Studies Performed in Oncologic Patients

Scientists explore the incidence of VAHL over time after the third COVID-19 vaccine administration and its relevance to [18F]FDG PET-CT interpretation of oncologic patients.

European Journal of Nuclear Medicine and Molecular Imaging
10/15/2021
Hepatic Artery Infusion Pump Combined With Systemic Chemotherapy for Patients With Liver Metastases From Breast Carcinoma

The efficacy and safety of HAI combined with systemic chemotherapy in patients with breast carcinoma liver metastases is evaluated through this study. 

Technology in Cancer Research & Treatment
10/16/2021
Added Value of Preoperative Contrast-Enhanced Mammography in Staging of Malignant Breast Lesions

Researchers evaluate the added value of CEM in preoperative staging of breast cancer in a randomized study.

BMC Cancer
10/18/2021
DLEU1 Promotes Oral Squamous Cell Carcinoma Progression by Activating Interferon-Stimulated Genes

Scientists find that DLEU1 exerts its oncogenic effects, at least in part, through activation of a series ISGs in OSCC cells.

Scientific Reports
10/14/2021
Defer Surgery in Operable Breast Cancer: How Long is Too Long?

Researchers evaluate outcomes of surgery compared to PET in patients with non-advanced, operable invasive breast cancer to determine if PET as initial therapy may safely postpone surgery.

Breast Cancer
10/18/2021
Identification of Immune Subtypes for Predicting the Prognosis of Patients in Head and Neck Squamous Cell Carcinoma

A series of bioinformatic approaches were used to identify HNSCC immune subtypes and investigate their underlying immune characteristics that detects potentially targetable ICB subtypes. 

Technology in Cancer Research & Treatment
10/16/2021
Medical Student Education Through Flipped Learning and Virtual Rotations in Radiation Oncology During the COVID-19 Pandemic

The development of virtual education platforms can establish a unique niche within medical education, especially within crisis periods. 

Radiation Oncology
10/16/2021
Subcutaneous Immunoglobulin Replacement for Treatment of Humoral Immune Dysfunction in Patients With Chronic Lymphocytic Leukemia

Researchers determine the prevalence of humoral immunodeficiency in patients with CLL and serum IgG ≥ 400 mg/dL & evaluate the efficacy of SCIG...

PLOS ONE
10/15/2021
Evaluation of DIBH and VMAT in Hypofractionated Radiotherapy for Left-Sided Breast Cancers After Breast-Conserving Surgery

Scientists evaluated the effects of DIBH irradiation & VMAT plans under DIBH on OAR dose deposition through a comparison of dosimetric parameters of OARs...

Technology in Cancer Research & Treatment
10/16/2021
PKI-587 Enhances Radiosensitization of Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Pathways and DNA Damage Repair

Researchers evaluate the role of the dual PI3K/mTOR inhibitor, PKI-587, on radiosensitization of HCC and its possible mechanism. 

PLOS ONE
10/19/2021
Influence of Autophagy Inhibition on Lung Adenocarcinoma Cell Migration and Invasion Ability, and Efficacy of Gefitinib

3 types of lung adenocarcinoma cells are selected to explore the influence of autophagy inhibition on the migration and invasion of lung adenocarcinoma cells...

 

Technology in Cancer Research & Treatment
10/16/2021
Development of a New poly-ε-caprolactone With Low Melting Point for Creating a Thermoset Mask Used in Radiation Therapy

In radiotherapy for head and neck cancer, a patient-specific thermoplastic mask is created to improve the patient’s positional accuracy.

Scientific Reports
10/14/2021
GNG7 and ADCY1 as Diagnostic and Prognostic Biomarkers for Pancreatic Adenocarcinoma Through Bioinformatic-Based Analyses

Researchers work to screen out the genes that have diagnostic and prognostic significance for PAAD through downloading the GSE55643 and GSE15471 mRNA expression profiles from the GEO database. 

Scientific Reports
10/14/2021
Systemic Immune-Inflammation Index is a Promising Non-Invasive Biomarker for Predicting the Survival of Urinary System Cancers

This meta-analysis aimed to explore the prognostic significance of pre-treatment SII in tumours of the urinary system.

Annals of Medicine
10/14/2021
Assessment of the Clinical Utility of Circulating Tumor Cells at Different Time Points in Predicting Prognosis of Patients With Small Cell Lung Cancer

Scientists investigate the prognostic significance of different time points of CTCs in SCLC.

Cancer Control
10/15/2021
Comprehensive Analysis of IGFBPs as Biomarkers in Gastric Cancer

This study aimed to explore IGFBPs and their prognostic value as markers in gastric cancer.

Frontiers in Oncology
10/21/2021
Personalized Interventions Reduce Chemotherapy-Related Toxicity Among Older Adults

A randomized clinical trial showed use of personalized interventions significantly reduced grade 3 or higher chemotherapy-related toxicity among patients with cancer aged 65 years or older. 

Healio
10/20/2021
Nut Consumption Associated With Survival Benefit Among Long-Term Breast Cancer Survivors

Nut consumption appeared associated with higher survival rates among long-term breast cancer survivors and should be emphasized as a modifiable lifestyle factor in survivor guidelines. 

Healio
10/20/2021
Genomic Markers May Predict Clinical Outcomes in Patients With B-Cell Acute Lymphoblastic Leukemia

Among adult patients with BCRABL1 negative B-ALL, genomic evaluation may lead to improved risk assessment, according to research published in Blood.

Hematology Advisor
10/20/2021
Schizandrin A Can Inhibit Non‑Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest, Apoptosis and Autophagy

Research suggests that SchA exerted inhibitory effects on NSCLC physiology by inducing cell cycle arrest and apoptosis and partially induces autophagy.

International Journal of Molecular Medicine
10/12/2021
The TCI Clinical Encounter Program for PhD Students in Cancer Biology

Clinical rotations are often not included in graduate-level cancer biology curricula; however basic insight into clinical oncology is crucial for developing research that meets unmet patient needs.

Journal of Cancer Education
10/14/2021
Identifying Modifiable Risk Factors of Lung Cancer

While lung cancer incidence rate has recently declined, it is still far from satisfactory and its potential modifiable risk factors should be explored.

PLOS ONE
10/18/2021
Plasma Lipidomic Profiles of Kidney, Breast and Prostate Cancer Patients Differ From Healthy Controls

Lipidomic changes are investigated and visualized using various MDA tools, such as PCA, orthogonal projection to latent structures discriminant analysis, and ROC. 

Scientific Reports
10/13/2021
Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients

To investigate the potential benefits and safety of acupuncture on managing side effects induced by drug therapies in patients with breast cancer using a PRISMA standard systematic review...

Evidence-Based Complementary and Alternative Medicine
10/12/2021
A Mixed Methods Population Health Approach to Explore Radon-Induced Lung Cancer Risk Perception in Canada

Researchers employe a MM approach to understand determinant perceptions of the risk as well as the micro & macro level factors that motivate residents to adopt preventive actions.

Cancer Control
10/12/2021
Global Access to Radiotherapy for Lung Cancer

This webinar describes the current landscape and challenges to deliver RT for lung cancer, with an emphasis on low-and middle-income countries and geographically underserved regions of high-income countries.

09/22/2021
Advances in Radiation Therapy in Stage III NSCLC

Oncology specialists from a lung multidisciplinary team discuss challenges associated with radiation therapy in Stage III NSCLC.

09/07/2021
Challenges in Advanced Lung Cancer Diagnosis During the COVID-19 Pandemic

Doctors and researchers collaborate to create individualized management for lung cancer patients to protect them from COVID-19.

Technology in Cancer Research & Treatment
10/16/2021
Updates in Radiotherapy at ELCC 2021

In this discussion, Dr Umberto Ricardi outlines the latest developments in RT for patients with lung cancer, highlighting the ability to improve treatment of brain metastases with radiosurgery...

04/12/2021
The Effect of Exchanging Drawings With Peers on the Happiness of Children With Cancer, Aged 7–11 Years

Improving the mental status of children with cancer is part of a nurses’ duties and is achieved in different ways, here nurses combine drawing with peer interaction to improve mental status.

PLOS ONE
10/15/2021
Future Perspectives on Radiation Oncology in Lung Cancer

Dr Umberto Ricardi discusses the management of patients with lung cancer who have brain metastases and the importance of precision medicine in treating these patients.

04/12/2021
Additional Radiotherapy With or Without Chemotherapy Following Endoscopic Resection for Stage I Esophageal Carcinoma

Scientists retrospectively analyzed the clinical outcomes of stage I EC patients with high-risk factors who received RT at our institution after ER.

 

Technology in Cancer Research & Treatment
10/16/2021
Patterns of Relapse After Radiotherapy in SCLC and Future Treatment Strategies

Dr Sanjay Popat discusses the findings of a subset analysis of the CONVERT trial investigating patterns of relapse following thoracic radiotherapy in patients with limited-stage SCLC.

04/01/2021
The Mechanism of miR-141 Regulating the Proliferation and Metastasis of Liver Cancer Cells by Targeting STAT4

The expression of miRNA-141 in hepatocellular carcinoma cells & the effect of targeting STAT4 on the proliferation, migration, & invasion on those cells were detected using qRT-PCR, MTT.

Journal of Oncology
10/12/2021
Clinicopathological Features and Survival of Adolescent and Young Adults with Cervical Cancer

Researchers explore the clinicopathological characteristics and find a meaningful method to predict the prognosis of young women with cervical cancer.

Cancer Control
10/14/2021
Targeted Prostate Cancer Screening Could Benefit Men With Inherited Cancer Syndrome

Men who inherit an increased risk of cancer through "Lynch syndrome" could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer.

Medical Xpress
10/19/2021
Integration Analysis of m6A Related Genes in Skin Cutaneous Melanoma and the Biological Function Research of the SPRR1B

Research provides a new view for the comprehensive action of m6A regulatory factors & for the first time finds SPRR1B can promote the proliferation, invasion & migration of melanoma cells <

Frontiers in Oncology
10/19/2021
Bioinformatics Analysis of ZBTB16 as a Prognostic Marker for Ewing's Sarcoma

The purpose of this study was to identify novel biomarkers for the prognosis of Ewing's sarcoma based on bioinformatics analysis.

BioMed Research International
10/06/2021
Phase II Study of Dacarbazine Given With Modern Prophylactic Anti-Emetics and Growth Factor Support to Patients With Metastatic, Resistant Soft Tissue, and Bone Sarcoma

Investigators hypothesized that administration of potent prophylactic anti-emetics and growth factors with dacarbazine would markedly reduce the proportion of patients who experience...

Rare Tumors
10/08/2021
MYL2 as a Potential Predictive Biomarker for Rhabdomyosarcoma

The discovery of biomarker is expected to be the direction of targeted therapy, providing a new direction for the precise treatment of RMS.

Medicine
10/01/2021