Supportive Care

Supportive Care

COVID-19 Vaccine Boosters Appear Effective in Patients With Thoracic Cancer

COVID-19 vaccines appear effective in patients with thoracic cancer, and a third shot is beneficial in those with low antibody titers, according to a new study.

Cancer Therapy Advisor
Researchers Look at Access to Essential Cancer Drugs on a Global Scale

A recent study in The Lancet Oncology looked at whether the cancer therapeutics in the Essential Medicines List were aligned with the needs of oncologists worldwide.

The ASCO Post
Immunogenicity of SARS–CoV-2 Vaccines in Patients With Cancer

The CANVAX Cohort Study found that immunogenicity varied among vaccines and that both antibody concentrations and neutralization titers were lower than those in healthy controls. 

The ASCO Post

Fasting-Mimicking Diet Safe, May Benefit Patients on Anticancer Therapy

A cyclic, 5-day fasting-mimicking diet appeared safe and showed potential to improve outcomes among patients on anticancer therapy for different tumor types, according to new study results. 

Pre-Existing Cardiovascular Disease Increases Risk of Atrial Arrhythmia and Mortality in Cancer Patients Treated With Ibrutinib

Researchers investigate the incidence of new-onset atrial fibrillation after ibrutinib initiation in patients with underlying CVD. 

Acceptability and Appropriateness of a Clinical Pathway for Managing Anxiety and Depression in Cancer Patients

Scientists explore differences between trial arms (core versus enhanced) in these outcomes to determine whether implementation intensity impacts perceptions of the CP itself.

BMC Health Services Research
Undertaking General Practice Quality Improvement to Improve Cancer Screening

A qualitative approach was used to interview 18 general practice staff and five Primary Health Network staff to understand their experiences with these quality improvement initiatives.

BMC Family Practice
New Resilience Instrument for Family Caregivers in Cancer

Scientists validate the 10-item Resilience Scale Specific to Cancer in FCs using multidimensional item response theory analysis.

Health and Quality of Life Outcomes
Cell-Morphodynamic Phenotype Classification With Application to Cancer Metastasis Using Cell Magnetorotation and Machine-Learning

Researchers define cell morphodynamics using a dynamic histology method which is based on multiplexed Cell Magneto-Rotation and Machine Learning. 

Study Explores Efficacy & Safety of Tanezumab for Cancer Pain

New research suggests that subcutaneous tanezumab improved metastatic cancer-related bone pain when compared with placebo, according to data recently presented at the ESMO Congress 2021. 

Oncology Times - Latest Articles
Maternal Deaths Among Patients With Cancer in the United States

A population-based analysis of maternal death among cancer patients was conducted in a modern cohort from the SEER database to characterize the risks of maternal deaths in cancer patients... 

Digital Symptom Monitoring Can Improve Outcomes of Cancer Care

Digital symptom monitoring using patient-reported outcome surveys can improve clinical outcomes in patients with cancer, according to new research. 

Cancer Therapy Advisor
Opioid Regulations May Result in Poorer Pain Management for People With Terminal Cancer

Opioid use among people dying of cancer declined substantially from 2007 to 2017, according to study results published in Journal of Clinical Oncology.

Can Quality of Life Assessments Predict PFS, OS Across Cancer Types?

Studies have suggested that quality of life assessments can predict PFS and OS in patients with cancer, though this doesn’t appear to hold true for all cancer types or in all treatment settings. 

Cancer Therapy Advisor
Most Therapies Tested in Phase 3 Cancer Trials Fail to Confer Meaningful Survival Benefit

More than 80% of therapies tested in phase 3 oncology trials did not demonstrate clinically meaningful benefit in extending survival, according to results of a study published in JNCCN. 

Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer

Researchers correlate the immunogenicity and reactogenicity of current US FDA Emergency Use Authorization vaccines in a large cohort of approximately 1,000 patients enrolled in the CANVAX study.

Journal of Clinical Oncology
ROS-Activated Homodimeric Podophyllotoxin Nanomedicine With Self-Accelerating Drug Release for Efficient Cancer Eradication

Researchers prove integrating multiple mechanisms into a single PTV-NPs would overcome the drawbacks of POD, reduce the side effects of POD, and substantially improve therapeutic efficacy.

Drug Delivery
Developing, Implementing, and Validating a Social Toxicity Assessment Tool of Cancer

Researchers create a multidimensional tool to assess the social toxicity of cancer on affected patients in terms of social relations, social activities, and economic impact.

JCO Global Oncology
Lack of Insurance ’Completely’ Accounts for Lower Cancer Screening Rates Among Unemployed

Unemployment appeared associated with a lower likelihood of having health insurance and of being up to date on cancer screening tests, according to results of a study published in Cancer.<

Risks and Benefits Associated With Gastrostomy Tubes for Patients With Cancer

In a JNCCN studyresearchers examined over 200 patients with gastrostomy tubes and highlighted the need for a multidisciplinary approach to palliative care decision-making for patients...

The ASCO Post
Cancer Treatment, Rather Than Cancer Itself, May Increase Risk of Adverse COVID-19 Outcomes

Cancer patients who have not received recent cancer treatment have similar COVID-19 outcomes as patients without cancer, after adjusting for potential confounders. 

Cancer Therapy Advisor
Cardiovascular Warnings Common But Slower to be Issued for FDA-Approved Cancer Drugs

Although more than 25% of contemporary FDA-approved cancer therapies required cardiovascular warnings, post-marketing issuance of the warnings trailed clinical approval by several years...

A Comparison of the Food and Drug Administration’s and Health Canada’s Regulatory Decisions About Failed Confirmatory Trials for Oncology Drugs

This study compares decisions by the FDA and Health Canada about oncology drugs that were approved using either Accelerated Approval (FDA) or NOC/c (Health Canada), that failed confirmatory trials.

Journal of Pharmaceutical Policy and Practice
Daily Caloric Restriction Limits Tumor Growth More Effectively Than Caloric Cycling Regardless of Dietary Composition

Researchers find that daily CR provides greater protection against tumor growth and metastasis to the lung, which may be in part due to the unique immune signature observed with daily CR.

Nature Communications
Infrared Molecular Fingerprinting of Blood-Based Liquid Biopsies for the Detection of Cancer

Researchers lay the foundation for high-throughput onco-IR-phenotyping of four common cancers, providing a cost-effective, complementary analytical tool for disease recognition.

Patient Powered Research: An Approach to Building Capacity for a Hardly Reached Patient Population to Engage in Cancer Research

A community engaged research approach was used to establish a PAC rep of the patient population served by a safety net hospital cancer center to explore inequalities in cancer trial participation. 

Research Involvement & Engagement
Building a Biopsychosocial Model of Cancer-Related Fatigue

This longitudinal study builds a biopsychosocial model of CRF by simultaneously investigating anthropometric, clinical, biological, physical, psychological and sociological parameters using SEM.

BMC Cancer
Study Finds Prior Authorization Costs Academic Radiation Oncology Clinics More Than $40 Million Every Year

The time required to secure prior authorization approvals for RT equates to a financial impact of more than $40 million annually for academic medical centers according to a new ASTRO study.

The ASCO Post
Traditional Herbal Medicine, Sipjeondaebo-Tang, for Cancer-Related Fatigue

This randomized, placebo-controlled, preliminary study evaluated SDT for cancer-related fatigue, which is the most common symptom experienced by patients with cancer.

Integrative Cancer Therapies
Second Dose of COVID-19 Vaccine Not Enough for Some Patients With Cancer

Researchers find that when compared with healthy individuals, patients with cancer have lower levels of anti-spike protein (anti-S) antibodies after COVID-19 vaccination.

Cancer Therapy Advisor
Many Breast Cancer Patients Use Cannabis for Symptom Relief

A new survey of US patients with breast cancer found that 42% were using cannabis, primarily to relieve side effects associated with treatment, such as pain, anxiety, nausea, and insomnia. 

Thoracic Oncologists Adopt Telehealth During COVID-19 Pandemic

Nearly two-thirds of thoracic oncologists surveyed indicated they used telehealth tools for the first time during the COVID-19 pandemic. 

Oncology Times - Latest Articles
Changes in BMI, Weight Linked to Survival in Endometrial Cancer

Assessing endometrial cancer survivors after diagnosis shows changes in weight or body BMI around the time of endometrial cancer diagnosis is associated with reduced survival.

Cancer Therapy Advisor

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