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Cancer Therapy Advisor

Cancer Therapy Advisor
Seminal Vesicle-Sparing in Radical Cystectomy Shown to Improve Outcomes

Seminal vesicle sparing at radical cystectomy provides good oncologic outcomes and helps to preserve urinary continence and sexual function in well-selected patients with bladder cancer, a new stud

Cancer Therapy Advisor
04/02/2021
Patterns in the Development of Melanoma Across Body Sites

An international research team examined patterns in the development of melanoma in patients in Australia and the United Kingdom and shed light on possible relationships by anatomical site.

Cancer Therapy Advisor
03/24/2021
Higher Rates of Sustained MRD Negativity Seen With Daratumumab-Containing Regimens Versus SOC in R/R Multiple Myeloma

Evaluation of MRD in the POLLUX and CASTOR trials shows that daratumumab-based regimens induce higher rates of sustained MRD negativity vs standard-of-care combination therapies.

Cancer Therapy Advisor
02/16/2021
Adjuvant Sequential Chemoradiation Affords Superior DFS Benefit Versus CCRT, RT in Early-Stage Cervical Cancer

Sequential chemoradiation was found to result in longer DFS and a lower risk for cancer death compared with concurrent chemoradiation or RT alone in the postoperative...

Cancer Therapy Advisor
01/28/2021
Men at Increased Risk for Mortality Following Allogeneic Hematopoietic Stem Cell Transplant

GVHD and age at transplant were significantly associated with mortality risk.

Cancer Therapy Advisor
12/05/2020
Durable Responses Seen With Odronextamab in Refractory B-Cell NHLs

Odronextamab, demonstrated promising antitumor activity and an acceptable safety profile — including with cytokine release syndrome (CRS)–mitigating strategies — among patients with B-cell NHLs.

Cancer Therapy Advisor
12/07/2020
High False-Negative RT-PCR Rates for SARS-CoV-2 Observed in Patients With Hematologic Malignancies

Hematologic malignancy was associated with more severe COVID-19 and high false-negative SARS-CoV-2 rates as measured by standard RT-PCR testing...

Cancer Therapy Advisor
12/06/2020
BCMA-Directed CAR-T Therapy Shows Clinical Activity in Multiple Myeloma

An investigational CAR-T therapy that targets B-cell maturation antigen showed clinical activity in heavily pretreated patients with relapsed/refractory multiple myeloma...

Cancer Therapy Advisor
12/07/2020
G-CSF Pretreatment Ameliorates the Activity of an Autologous DC-Based Vaccine in Melanoma

Pretreatment with granulocyte colony stimulating factor failed to improve dendritic cell collection for an autologous DC-based vaccine for advanced, resectable melanoma...

Cancer Therapy Advisor
11/13/2020
DLL3-Targeted BiTE Shows Antitumor Activity in SCLC

An anti-DLL3 bispecific T-cell engager demonstrated antitumor activity with an acceptable safety profile, according to interim results of a phase 1 study presented at the virtual... 

Cancer Therapy Advisor
11/13/2020
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