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JAMA Oncology

JAMA Oncology
Prognosis Associated With Luminal and Basal Subtypes of Metastatic Prostate Cancer

Researchers developed an approach specific to the metastatic prostate cancer disease state to identify luminal (B) and basal subtypes in 634 mCRPC samples from 4 independent clinical cohorts.

JAMA Oncology
09/23/2021
Risk of Pancreatic Cancer Among Individuals With Pathogenic Variants in the ATM Gene

Researchers work to estimate age-specific penetrance of pancreatic cancer in individuals with a pathogenic variant in the ATM gene.

JAMA Oncology
09/16/2021
Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-Risk Breast Cancer

Researchers study the pattern and prognosis for residual cancer burden after neoadjuvant chemotherapy in breast cancer patients. 

JAMA Oncology
09/16/2021
Projected Association of HPV Vaccination With Oropharynx Cancer Incidence in the US, 2020-2045

This study examines the association of HPV vaccination with future oropharynx cancer incidence in the US.

JAMA Oncology
09/02/2021
Effect of Cisplatin and Gemcitabine With or Without Berzosertib in Patients With Advanced Urothelial Carcinoma

Does inhibition of ataxia telangiectasia and Rad3 complement cisplatin-based chemotherapy for metastatic urothelial cancer?

JAMA Oncology
08/26/2021
Single-Fraction vs Multifraction Stereotactic Ablative Body Radiotherapy for Pulmonary Oligometastases

This study seeks to answer the question: Is single-fraction or multifraction SABR optimal for the treatment of patients with 1 to 3 oligometastases to the lung?

JAMA Oncology
08/29/2021
Effects of Exercise on Cardiorespiratory Fitness and Biochemical Progression in Men With Localized Prostate Cancer Under Active Surveillance

This study seeks to answer the question: Does a high-intensity interval training program improve cardiorespiratory fitness and delay the biochemical progression of prostate cancer...

JAMA Oncology
08/19/2021
Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer

This study aims to answer the question: Is concurrent chemoradiotherapy with S-1 an effective and tolerable treatment for older patients with esophageal cancer?

JAMA Oncology
08/05/2021
Metformin in Combination With Chemoradiotherapy in Locally Advanced Non–Small-Cell Lung Cancer

This study seeks to answer the question: Could the addition of metformin to CRT, as a concurrent treatment as well as consolidation therapy, improve outcomes in patients without diabetes who have..

JAMA Oncology
07/29/2021
Nivolumab Plus Ipilimumab vs Nivolumab for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer

Combination therapy with nivolumab and ipilimumab is currently only indicated as first-line therapy in patients with advanced non–small-cell lung cancer.

JAMA Oncology
07/15/2021
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