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Biomedicines

Biomedicines

We evaluated the efficacy of two tetrapeptidic doxo prodrugs (PhAc-ALGP-Dox or CBR-049 and CBR-050) that are locally activated by enzymes expressed in the tumor environment...

Biomedicines
04/06/2022

Researchers found that BETi, similar to ATO + ATRA, induced differentiation and apoptosis which was TP53 independent in the NPM1c cell line OCI-AML3 and primary cells. 

Biomedicines
11/17/2021

The aim of this study is to determine the expression and function of NECTIN4 in cSCC.

Biomedicines
03/30/2021

The aim of this review is to summarize the major studies that have investigated the role of microRNAs as mediators of resistance to targeted therapies currently in use in GI neoplasms...

Biomedicines
03/21/2021

This study discusses the recent SCLC studies of CTCs, cfDNA and other liquid biopsy biomarkers, and discusses the future utility of liquid biopsy in the clinical management of SCLC.

Biomedicines
01/07/2021

This article summarizes recent clinical developments related to mithramycin and postulates a role for the use of mithramycin, or its analog, in the treatment of platinum-resistant ovarian cancer.

Biomedicines
01/12/2021

This review presents a literature overview of BCC from pathophysiology to novel therapeutic approaches.

Biomedicines
10/23/2020
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