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Cancer Cell International

Cancer Cell International
Prognostic Value of a Novel Biomarker Combining DNA Ploidy and Tumor Burden Score for Initially Resectable Liver Metastases From Patients With Colorectal Cancer

The prognostic value of DNA ploidy, stroma fraction and nucleotyping of initially resectable liver metastases from patients with CRLM is examined by researchers. 

Cancer Cell International
10/23/2021
Incidence of Suicide Among Adolescent and Young Adult Cancer Patients

As the survival rates of cancer patients continue to increase, most cancer patients now die of non-cancer causes, this study characterizes suicide mortality among AYA patients in the US...

Cancer Cell International
10/18/2021
Establishment and Drug Screening of Patient-Derived Extrahepatic Biliary Tract Carcinoma Organoids

Researchers establish a series of PDOs from eBTC to determine whether the physiological structure and genetic profiles are maintained in these cultures. 

Cancer Cell International
10/02/2021
Serum GGT/ALT Ratio Predicts Vascular Invasion in HBV-Related HCC

Research determines the role of the GGT/ALT ratio in the prediction of vascular invasion and survival outcomes in patients with HBV-related HCC.

Cancer Cell International
09/28/2021
ALDOA Inhibits Cell Cycle Arrest Induced by DNA Damage via the ATM-PLK1 Pathway in Pancreatic Cancer Cells

Researchers probed the potential role of ALDOA in the cell cycle arrest induced by DNA damage in pancreatic tumour cells and discovered that ALDOA participated in regulating the DDR...

Cancer Cell International
09/26/2021
Single Cell RNA-seq Data and Bulk Gene Profiles Reveal a Novel Signature of Disease Progression in Multiple Myeloma

Scientists complete a comprehensive analysis of scRNA-seq data and bulk gene expression profiles to reveal the development map of human MM cells...

Cancer Cell International
09/25/2021
Expression and Subcellular Localization of Discoidin Domain Receptor 1 (DDR1) Define Prostate Cancer Aggressiveness

Scientists examined the expression of DDR1 in prostate cancer (PCa), and assessed its potential value as a prognostic marker, as a function of grade, stage and other clinicopathologic parameters.

Cancer Cell International
09/21/2021
The Cholesterol Esterification Inhibitor Avasimibe Suppresses Tumour Proliferation and Metastasis via the E2F-1 Signalling Pathway in Prostate Cancer

The main purpose of this study is to explore the effects and the underlying mechanisms of avasimibe in prostate cancer.

Cancer Cell International
08/30/2021
Long Non-Coding RNA NEAT1 Facilitates the Growth, Migration, and Invasion of Ovarian Cancer Cells Via the let-7 g/MEST/ATGL Axis

The current study aims to investigate the role of the NEAT1/let-7 g axis in the growth, migration, and invasion of ovarian cancer cells and explore underlying mechanisms.

Cancer Cell International
08/20/2021
Plastin-3 is a Diagnostic and Prognostic Marker for Pancreatic Adenocarcinoma and Distinguishes From DLBCL

This study assessed differentially expressed genes and then bioinformatically and experimentally confirmed PLS3 to be able to predict pancreatic ductal adenocarcinoma prognosis and distinguish...

Cancer Cell International
08/04/2021
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