Journal of Translational Medicine

Journal of Translational Medicine
Niraparib Exhibits a Synergistic Anti-Tumor Effect With PD-L1 Blockade by Inducing an Immune Response in Ovarian Cancer

In this study, investigators examined the dynamic changes and responses of immune cells and cytokines during Niraparib treatment for ovarian cancer.

Journal of Translational Medicine
Development of a Two-Circular RNA Panel as Potential Prognostic Biomarker for Gastric Cancer

Scientists attempted to screen circRNAs that can be used to predict postoperative recurrence and survival in patients with GC.

Journal of Translational Medicine
Nuclear HER3 Expression Improves the Prognostic Stratification of Patients With HER1 Positive Advanced Laryngeal Squamous Cell Carcinoma

Scientists conducted this retrospective observational study on two series of locoregionally advanced LSCC patients treated with BioRT with cetuximab and salvage or upfront surgery...

Journal of Translational Medicine
Low CCL19 Expression is Associated With Adverse Clinical Outcomes for Follicular Lymphoma Patients Treated With Chemoimmunotherapy

This study examined hub genes associated with prognosis in follicular lymphoma treated with first-line rituximab combined with chemotherapy.

Journal of Translational Medicine
Evaluating Predictive Factors for Toxicities Experienced by Head & Neck Cancer Patients Undergoing Radiotherapy

The purpose of this study is to evaluate if HPV status serves as an independent predictor of early and late dysphagia outcomes when considered alongside standard patient characteristics...

Journal of Translational Medicine
Inhibition of EZH2 by Chidamide Exerts Antileukemia Activity and Increases Chemosensitivity Through Smo/Gli-1 Pathway in Acute Myeloid Leukemia

Aberrant activation of HDACs results in uncontrolled proliferation and blockade of differentiation, and HDAC inhibition has been investigated as epigenetic therapeutic strategy against AML.

Journal of Translational Medicine
High Lymphocyte Population-Related Predictive Factors for a Long-Term Response in Non-Small Cell Lung Cancer Patients Treated With Pemetrexed

This study investigates the clinical characteristics and predictive factors in patients with advanced NSq-NSCLC who underwent long-term PEM maintenance therapy.

Journal of Translational Medicine
Genome-Wide Analysis Identifies Critical DNA Methylations Within NTRKs Genes in Colorectal Cancer

The following study investigates the methylation and expression profiles and prognostic value of NTRKs gene in colorectal cancer.

Journal of Translational Medicine
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