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ASH Clinical News

ASH Clinical News
Modified EASIX Score Predicts CRS and ICANS Before Severe Symptoms in Patients With B-Cell Malignancies

A modified version of the EASIX score, when calculated prior to and soon after CAR T-cell infusion, predicted severe CRS and ICANS before their occurrence. 

ASH Clinical News
11/01/2021
Routine Screening for Germline Variants in Patients With AML

Nearly 14% of adult patients with acute myeloid leukemia have pathogenic or likely pathogenic germline variants that make them susceptible to myeloid malignancies.

ASH Clinical News
11/01/2021
Idecabtagene Vicleucel Approved for Relapsed or Refractory Multiple Myeloma

The FDA has approved ide-cel as the first BCMA-directed CAR T-cell therapy for the treatment of adult patients with R/R MM who have received four or more prior lines of therapy, including...

ASH Clinical News
05/01/2021
Cellular Therapies Hold Promise in Myeloid Malignancies

A recent spate of approvals of targeted treatments, such as FLT3 and IDH1/2 inhibitors for acute myeloid leukemia, introduce major changes in the treatment of myeloid malignancies. 

ASH Clinical News
05/01/2021
R2CHOP Benefits Patients With Untreated Diffuse Large B-Cell Lymphoma, Regardless of Subtype

For patients with previously untreated DLBCL, adding lenalidomide to the combination of R-CHOP reduces the risk of progression or death by 34%.

ASH Clinical News
05/01/2021
High- and Low-Dose Rivaroxaban Versus Aspirin for Women With VTE and Heavy Menstrual Bleeding

Results of a substudy published in Research and Practice in Thrombosis and Haemostasis suggest there is no statistically significant difference in menstrual hemorrhage in patients with VTE

ASH Clinical News
05/01/2021
FDA Grants Breakthrough Therapy Designation to Asciminib for CML

The FDA has granted breakthrough therapy designation to asciminib for the treatment of adults with Philadelphia chromosome-positive chronic-phase CML that is resistant to...

ASH Clinical News
04/01/2021
Melphalan Flufenamide Receives Accelerated Approval for Relapsed/Refractory Multiple Myeloma

Melphalan flufenamide, in combination with dexamethasone, has received accelerated approval from the FDA for the treatment of adult patients with relapsed or refractory MM who have received...

ASH Clinical News
04/01/2021
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