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Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis

This study shows that in addition to cancer cell EMT, ovarian cancer cell metastasis relies on an epigenomic mesenchymal-to-epithelial transition in host mesenchymal stem cells.

12/18/2020
Ovarian Cancer Cells Cooperate to Metastasize

The team isolated subpopulations of cells from human ovarian tumors and found that none had the ability to form metastatic tumors on its own. 

Oncology Times - Latest Articles
12/20/2020

Primary Breast Tumors Often Switch HER2 Status on Relapse

A substantial proportion of primary breast tumors that are HER2 negative (HER2-0) switch to showing HER2-low expression upon relapse, a first-of-its-kind study suggests.

Medscape
05/11/2021
Pembrolizumab Plus Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Given each drug's single agent activity and unique mechanism of action, this study aims to evaluate the anti-tumour activity of PD-1 blockade with EGFR inhibition in recurrent or metastatic HNSCC.<

The Lancet Oncology
05/11/2021
Understanding Socioeconomic Disparities in Lung Cancer Care

A recent study finds that sociodemographic factors such as race, marital, income, and insurance status are associated with disparities in the receipt of lung cancer treatment, per findings...

Oncology Times - Latest Articles
04/01/2021

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